introduction: the current study aimed to elucidate the role of preparatory cognitive control in decision making and its neural correlates using functional magnetic resonance imaging (fmri). to this effect, by employing a series of new cognitive tasks, we assessed the role of preparatory cognitive control in monetary (risky) decision making. methods: the participants had to decide between a risk...

PurposeThe ‘chapeau de gendarme’ (CDG) sign, characterised by a symmetric down-turned mouth, has been considered as semiological hallmark of focal epileptic seizures with cingulate or insular involvement. We report three cases in which the CDG sign featured habitual seizures.MethodsThe epileptogenic zones these patients were localized lateral prefrontal cortex video-stereoelectroencephalography...

conclusion distinct neurochemical and histological structure changes (cortico-striatal-thalamic-cortical cycle) exist in patients with first-episode ocd. 1h-mrs is capable of identifying these changes by assessing metabolic abnormalities. objectives this study aims to use magnetic resonance spectroscopy (mrs) to discover substance-metabolism abnormalities of brain circuits in patients with firs...

OBJECTIVE The dorsolateral prefrontal cortex and the anterior cingulate cortex are critical components of the brain circuitry underlying executive control. The objective of this study was to investigate control-related dorsolateral prefrontal cortex functioning and conflict-related anterior cingulate cortex functioning in a group of never medicated first-episode schizophrenia patients to determ...

Empathy refers to the ability to perceive and share another person's affective state. Much neuroimaging evidence suggests that observing others' suffering and pain elicits activations of the anterior insular and the anterior cingulate cortices associated with subjective empathetic responses in the observer. However, these observations do not provide causal evidence for the respective roles of a...

introduction: a fixed hemodynamic response function (hrf) is commonly used for functional magnetic resonance imaging (fmri) analysis. however, hrf may vary from region to region and subject to subject. we investigated the effect of locally estimated hrf (in functionally homogenous parcels) on activation detection sensitivity in a heroin cue reactivity study. methods: we proposed a novel explora...

BACKGROUND Early atrophy of the cingulate cortex is a feature of both behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD), with degeneration of the anterior cingulate region increasingly recognized as a strong predictor of bvFTD. The total number of neurons in this region, rather than the density of neurons, is associated with mood disturbance in other dementias, alt...

Background Cholinergic systems regulate the synaptic transmission resulting in the contribution of the nociceptive behaviors. Anterior cingulate cortex is a key cortical area to play roles in nociception and chronic pain. However, the effect of the activation of cholinergic system for nociception is still unknown in the cortical area. Here, we tested whether the activation of cholinergic recept...