background: opioid analgesics are the mainstay of the treatment of postoperative pain. appropriate monitoring of patients receiving opioid analgesics is essential to detect those with side effects such as respiratory depression. the discovery of acetaminophen as a cox-3 variant may represent a primary central mechanism by which acetaminophen decrease pain. the aim of this study was to assess th...

m r v ( l n a a o s the United States struggles with healthcare reform, an opportunity exists to consider how pain research and pracice can serve as a model to inform the roader national reform and policy deate. Ensuring healthcare quality (ie, efectiveness, efficacy, and access to healthare) requires sound research to benefit ndividuals and society. Pain has reached pidemic proportions. The ep...