Formation of the basic antibiotic, K-582 was stimulated by supplying Metarrhizium anisopliae U-47 with several amino acids present in its structure. The addition of L-arginine to the basal medium resulted in the almost exclusive formation of K-582 B, while L-lysine increased K-582 A formation. Some carbon sources were observed to have effects similar to those obtained with the above mentioned a...

Introduction Varroa destructor Anderson & Trueman (2000) is an ectoparasitic mite which causes severe damage to Apis mellifera populations worldwide. Adult females of V. destructor feed directly on the haemolymph of honey bee pupae and can activate and transmit honeybee viruses. Infestation causes an increased prevalence of bee diseases and colony mortality, resulting in decline of honey produc...