نتایج جستجو برای: aniline derivatives

تعداد نتایج: 108338  

Journal: :Chemical & pharmaceutical bulletin 2004
Hideko Kawaki

In gas liquid chromatography (GLC), the relative retention values log gamma was mainly expressed by van der Waals energy (the sum of the dispersion E(dis) and repulsive E(rep) energies) to the interactions between monosubstituted benzene derivatives and the nonpolar stationary liquid as squalane. The single exception was that of anilines, and it was corrected by the electrostatic energy (E(ES))...

2015
Wei Zhao Yong Yang Ya-Xuan Zhang Chen Zhou Hong-Mei Li Ya-Ling Tang Xin-Hua Liang Tao Chen Ya-Jie Tang

This work aims to provide sampling of halogen-containing aniline podophyllum derivatives and their mode of action with an in-depth comparison among fluorine, chloride and bromide for clarifying the important role and impact of fluorine substitution on enhancing antitumor activity, with an emphasis on the development of drug rational design for antitumor drug. The tumor cytotoxicity of fluoride-...

Journal: :The Journal of the Society of Chemical Industry, Japan 1957

2018
Tarn C Johnson Bryony L Elbert Alistair J M Farley Timothy W Gorman Christophe Genicot Bénédicte Lallemand Patrick Pasau Jakub Flasz José L Castro Malcolm MacCoss Darren J Dixon Robert S Paton Christopher J Schofield Martin D Smith Michael C Willis

Sulfones feature prominently in biologically active molecules and are key functional groups for organic synthesis. We report a mild, photoredox-catalyzed reaction for sulfonylation of aniline derivatives with sulfinate salts, and demonstrate the utility of the method by the late-stage functionalization of drugs. Key features of the method are the straightforward generation of sulfonyl radicals ...

2012
Loredana Vacareanu Ana-Maria Catargiu Mircea Grigoras

An electrochemical study of two water-soluble aniline derivatives, N-(3-sulfopropyl) aniline (AnPS) and N-(3-sulfopropyl) p-aminodiphenylamine (DAnPS), in aqueous acidic electrolytic solutions containing different kinds of doping anions (Cl (-), SO(4) (2-), and ClO(4) (-)) was carried out. At sufficiently high anodic potential, the sulfonated aniline derivatives undergo oxidation processes yiel...

Journal: :Chinese Journal of Chemistry 2021

A gold(I)-catalyzed 6-endo-dig cyclization of aromatic 1,5-enyne was developed to synthesize 2-(naphthalen-2-yl)aniline. The functional group tolerance this examined systematically and a possible mechanism proposed. derivatization 2-(naphthalen-2-yl)aniline carried out facile access benzo[α]carbazole, benzo[c,h]cinnoline dibenzo[i]phenanthridine derivatives in divergent way.

2016
Eleonora Fava Anthony Millet Masaki Nakajima Sebastian Loescher Magnus Rueping

Visible-light-mediated photoredox-catalyzed aldimine-aniline and aldehyde-aniline couplings have been realized. The reductive single electron transfer (SET) umpolung of various carbonyl derivatives enabled the generation of intermediary ketyl and α-amino radical anions, which were utilized for the synthesis of unsymmetrically substituted 1,2-diamines and amino alcohols.

Journal: :The Journal of Organic Chemistry 2011

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