angioedema is an asymmetric non-pitting oedema on face, lips, tongue and mucous membranes; any delay in diagnosis and treatment can be fatal. treatment with lisinopril as an angiotensin converting enzyme (ace) inhibitor, can be a reason of angioedema. here we report a case who developed oral-facial edema four years after using lisinopril/hydrochlorothiazide. laryngeal oedema is a main cause of ...

Background: Controversial data concerning the elevation of serum angiotensin-converting enzyme in psoriasis are reported in the literature. In order to verify whether this abnormality exists in Iranian patients, we performed this study. Method: Serum angiotensin-converting enzyme level was measured in 40 psoriatics. According to clinical forms of psoriasis, patients were further divided into th...

introduction: in patients with uncomplicated primary hypertension (htn), angiotensin converting enzyme inhibitors (aceis) are considered as monotherapy. in some studies, cough was not related to age, sex, underlying disease, or drug dosage. however, in previous studies, the incidence of cough was greater in females than males. the aim of this study is to determine the incidence of captopril-ind...

angiotensin i-converting enzyme (ace) gene polymorphism; genotype dd or d allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (dn). we examined the frequency of ace gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without it) in tehran, iran. dna was extracted from the white blood cells and the i/d polymorphism of the ...

background: angiotensin i converting enzyme (ace) is a zinc metalloproteinase, converts ang-i to ang- ii, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. objective: to investigate the relationship between ace i/d polymorphism and type 2 diabetes in 261 iranian casecontrol pairs. methods: 170 patients (85 type 2 diabetics with nephropathy a...

background: sarcoidosis is a multisystem inflammatory disease of unknown origin with characterization of small granulomas. angiotensin-converting enzyme (ace) is a pathophysiologic marker of sarcoidosis. we present the ace insertion/deletion (i/d) polymorphism in correlation with serum ace level in iranian patients with sarcoidosis. methods: from jan 2014 to jan 2015, 102 iranian patients who h...

background: central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. our previous work showed that inhibition of angiotensin converting enzyme (ace) activity prior to induction of ischemia protected the brain from severe ischemia/reperfusion (i/r) injuries. this study evaluated the impacts of post-ischemic inhibition of ace, enalapril, on brain inf...

background: renal ischemia reperfusion (ir) injury has been a major source of concern during the past decades and angiotensin converting enzyme (ace) inhibitors have been successfully used to prevent this injury. there have been some controversial reports about the involvement of katp channels in the mechanism of action of ace inhibitors. in this study, we examined the effect of katp channel bl...

purpose it is well known that the effects of exercise training gives inter individual differences which might be due to genetic diversity. this study aims to explore the probable relation between angiotensin converting enzyme (ace) alleles and physical fitness parameters in elite athletes. methods twenty-nine national level indian army triathletes who volunteered for the study were taken as sub...