purpose: to present a case of pseudoxanthoma elasticum (pxe) with ocular involvement and visual loss. case report: a 36 year old male presented with severe visual loss since 2 years ago. on funduscopy peau d’orange appearance and angioid streaks were evident. the diagnosis of pxe was confirmed by skin biopsy of papular lesions on the neck. conclusion:  ocular findings may be helpful in the diag...

Background: The purpose of this study is to determine the incidence of angioid streak-associated choroidal neovascular membranes (CNV) in the UK and provide other epidemiological data, clinical characteristics, therapies used, and short-term outcomes following treatment of this condition. Procedure: This is a prospective multicenter cohort study. Patients newly diagnosed of angioid streaksassoc...

ANGIOID streaks of the retina were first described by Doyne (1889). They have since been the subject of much controversy. More than 200 cases have been reported in the literature, but histological studies have been few and the changes described have varied. The condition is frequently associated with pseudoxanthoma elasticum, with cardiovascular disease, and with Paget's disease of bone. A simi...

We report the favorable outcome of intravitreal injection of bevacizumab (Avastin) to treat choroidal neovascularisation (CNV) secondary to angioid streaks in an 82-year-old Chinese man. Within 2 weeks of bevacizumab injection, visual acuity improved from 20/40 to 20/25 and optical coherence tomography revealed complete resolution of CNV and retinal edema. The juxtafoveal hemorrhage nearly disa...

BACKGROUND Patients with angioid streaks are prone to developing subretinal hemorrhage after ocular or head injury due to the brittleness of Bruch's membrane. However, there have been no reports of any angioid streak patients in whom choroidal neovascularization occurred after vitrectomy surgery. We report herein a patient with angioid streaks who developed choroidal neovascularization after vi...

CASE REPORT We report a familial case of 2 brothers that suffered choroidal neovascularization (CNV) secondary to angioid streaks. They were both treated with a monthly intravitreal injection of ranibizumab (Lucentis(®)) for 3 months. Visual acuity was stabilized and fluorescein angiography revealed complete resolution of CNV. Neither recurrent CNV lesion nor new hemorrhages were reported durin...

The clinical significance and ophthalmoscopic features of angioid streaks have received considerable attention in the ophthalmic literature (Paton, I962; Paton, 1972; Connor, Juergens, Perry, Hollenhorst, and Edwards, I96I). Angioid streaks usually have a characteristic ophthalmoscopic appearance and diagnosis is easy. In some instances, however, they may be subtle or may simulate other more co...

Angioid streaks were observed in 21 of 242 patients with homozygous sickle cell disease. Two morphological types were observed. There is no evidence that angioid streaks in Jamaican patients are related to pseudoxanthoma elasticum.

Angioid streaks (AS) are the most common ocular manifestation in patients with pseudoxanthoma elasticum (PXE). The major cause of severe visual loss in patients with AS is choroidal neovascularization (CNV). We report the optical coherence tomography angiography (OCTA) findings of CNV in a patient with PXE and angioid streaks. A 51-year-old man with PXE presented with visual disturbance in his ...