نتایج جستجو برای: anaplastic astrocytoma
تعداد نتایج: 20945 فیلتر نتایج به سال:
chemokines are biologically active peptides involved in the pathogenesis of various pathologies including brain malignancies. they are amongst primitive regulators of the development of immune responses against malignant glial tumors. the present study aimed to examine the expression of cc chemokines in anaplastic astrocytoma and glioblastoma multiform patients at both mrna and protein levels. ...
We report on a 24-year-old woman who was diagnosed as having Maffucci syndrome with anaplastic astrocytoma. We analyzed the IDH1 and IDH2 mutations of enchondroma, hemangioma and anaplastic astrocytoma tissues and the same somatic mosaic mutation in IDH2 gene was identified in all these tissues. In addition, we identified additional mutation of the TP53 gene in anaplastic astrocytoma tissue but...
Anaplastic astrocytoma (AA; Grade III) and glioblastoma (GBM; Grade IV) are diffusely infiltrating tumors and are called malignant astrocytomas. The treatment regimen and prognosis are distinctly different between anaplastic astrocytoma and glioblastoma patients. Although histopathology based current grading system is well accepted and largely reproducible, intratumoral histologic variations of...
Malignant glioma comprises glioblastoma [World Health Organization (WHO) grade IV], anaplastic astrocytoma (WHO grade III), mixed anaplastic oligoastrocytoma (WHO grade III) and anaplastic oligodendroglioma (WHO grade III). Diagnosis after biopsy or tumor resection is made according to the revised WHO classification. Prognosis depends on tumor grade and histology. Glioblastoma carries the worst...
OBJECTIVE The number of evidences regarding the role of tumor stem cells (TSC) in the initiation and progression of high-grade astrocytomas became more and more numerous in the last years. This issue has been intensively tested in glioblastoma, but little attention has been paid for anaplastic astrocytoma. The main objective of this paper was to study the morphological characteristics of the xe...
Aims-To elucidate the implications of allelic loss on chromosome 10 in the malignant progression of human gliomas.Methods-Eight microsatellite loci (D10S249, D10S191, D10S210, D10S219, D10S246, D10S222, D10S221, and D10S212) were analysed for chromosomal deletions in histologically benign and malignant, including recurrent, gliomas. Of the 16 original tumours studied (two astrocytomas, nine ana...
BACKGROUND Survival of patients with anaplastic astrocytoma is highly variable. Prognostic markers would thus be useful to identify clinical subsets of such patients. Because specific genetic alterations have been associated with glioblastoma, we investigated whether similar genetic alterations could be detected in patients with anaplastic astrocytoma and used to identify those with particularl...
Purpose: The study was initiated to obtain epidemiologic data and information on anatomic distribution, clinical features and treatment results in patients with primary supratentorial anaplastic astrocytoma and glioblastoma multiform. Patients and Methods: Between January 2000 and January 2006, 113 primary high grade astrocytoma patients were eligible to evaluate clinical features. Radiotherapy...
Multiple primitive intracranial tumors with different histological characteristics are uncommon. Although coexistence of a medulloblastoma with glial tumors has been reported in children, medulloblastoma is rarely found in adults, especially those older than 40 years of age. We present an extremely rare case of a medulloblastoma developing in a 40-year-old male undergoing maintenance chemothera...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید