نتایج جستجو برای: amyloid beta
تعداد نتایج: 215549 فیلتر نتایج به سال:
neurological inflammatory diseases are developing rapidly. different factors involved in the pathogenesis of these diseases. in this article, we discuss some of the mechanisms are dealt with. an aberrant procedure of beta-amyloid precursor protein (bapp) to form neurotoxic beta-amyloid peptides and an accumulated insoluble polymer of beta –amyloid (ba) that forms the senile plaque. the above pr...
introduction: one of the most common markers in alzheimer’s disease (ad) is amyloid beta (aβ) plaques. anti-inflamm-atory agents including phagocytosis by immune cells, proteolytic enzymes and liver are known to decline the risk of aβ plaques formation. in the previous study we showed that aqueous extract of lavandula angusti-folia (lavender) improved memory deficits in alzheimeric rats. here, ...
alzheimer disease (ad) is a neurodegenerative disorder marked by cognitive and behavioral impairment. amyloid beta (aβ) peptides are involved in ad as the main component of amyloid plaques found in the brain. recent in vivo and in vitro studies have shown that there is a lot of substances that alter aβ pathogenesis of ad. aβ induces toxicity lead to increasing ros. in the other hand, 5-ht6 and ...
alzheimer’s disease (ad) is a neurodegenerative disease that is the most common type of dementia.ad includes 60_80% of dementia and most people with ad have more than 65 years old.ad causes losing neuronal activity by abnormal proteins. plaques of beta-amyloid and tangles of “tau” protein can lead to ad. recently evidence has found that ad may come from outside of central nervous system (cns) a...
Background and Objective: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and results from the extracellular accumulation of b-amyloid peptides and the resulting neuronal dysfunction. In this study, the role of nicotinic acetylcholine receptors, protein kinase B (PKB) and protein kinase M (PKM) were evaluated in order to examine the mechanism of the protective effe...
Background and Objective: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, in which cortical and hippocampus neurons death is the main target of neurodegeneration. In addition to extracellular beta amyloid accumulation and the production of neural tangles, one of effective factors in the pathology of Alzheimer's disease is vascular injury in the elderly including disturbanc...
platelet aggregation beta amyloid main causes inflammation of neurons in alzheimer’s disease. in fact, creating this inflammation due to inappropriate actions in blood brain barrier (bbb) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. the only thing that can be done to prevent and reduce pro-inflammatory factors such as cytokines ...
Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms. Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...
Platelet aggregation beta amyloid main causes inflammation of neurons in Alzheimer’s disease. In fact, creating this inflammation due to inappropriate actions in blood brain barrier (BBB) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. The only thing that can be done to prevent and reduce pro-inflammatory factors such as cyto...
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