Objective: To compare the rate of preterm delivery in patients who had an amniocentesis before and after 20 weeks gestation. Study Design: This is a single-center retrospective cohort study of patients referred for specialized sonogram between January 1, 2007 and December 31, 2009. Outcomes of patients who underwent amniocentesis at less than 20 0/7 weeks were compared to those who had amniocen...

INTRODUCTION The occurrence of early abortion after amniocentesis is a serious problem in the fields of obstetrics and gynecology, and it is always important to discover the factors influencing this phenomenon. The incidence rate has been reported in different studies, even up to about 10%. So far, no studies have been conducted in Iran on the effect of amniocentesis and related complications o...

BACKGROUND A major disadvantage of second trimester amniocentesis is that the result is usually available only after 18 weeks' gestation. Chorionic villus sampling (CVS) and early amniocentesis can be done between 9 and 14 weeks and offer an earlier alternative. OBJECTIVES The objective was to assess comparative safety and accuracy of second trimester amniocentesis, early amniocentesis, trans...

Of 655 Rh negative women without anti-D antibody in their serum at genetic amniocentesis, 361 delivered a Rh positive infant. Prophylactic treatment with anti-D immunoglobulin was not given at amniocentesis. The women were followed prospectively, being given a screening test for antibody after amniocentesis, at delivery, and six months later. Five of these 361 women yielded a positive test resu...

Objective: Amniocentesis is an invasive cytogenic test traditionally associated with a 1/200 procedure–related pregnancy loss rate. Recent studies have questioned the validity of the traditionally stated rate. The purpose of this study was to document the results of second-trimester genetic amniocentesis performed at our perinatalogy clinic. Study Design: A retrospective review of all the amnio...

OBJECTIVE We aimed to evaluate ductus venosus Doppler waveforms before and after amniocentesis in order to investigate any effect of amniocentesis on fetal myocardial hemodynamics. We also evaluated the umbilical artery, uterine artery and fetal mid-cerebral artery Doppler waveforms in order to investigate any relationship with ductus venosus Doppler changes. METHODS The study population cons...

BACKGROUND A primary goal of amniocentesis is the detection of trisomy 21 (Down syndrome- DS) in the fetus. This procedure involves a small risk of miscarriage. As the risk of DS increases with maternal age, screening tests (maternal serum triple test and others) and age are used to generate a risk assessment, and amniocentesis is offered to women with high risk. In Israel, amniocentesis is gov...

Objective Antenatal anxiety or maternal stress is a prevalent chronic mental disorder in pregnant women. We assessed the effect of maternal stress because of positive aneuploidy screening results on the alteration of uterine artery’s blood flow. MaterialsAndMethods A prospective cohort (one sample) study as a pilot study was done at a hospital in Tehran. Sixty pregnant women who were candidates...