Background and Aim: Due to the widespread use of antimicrobials in veterinary medicine and the increase in livestock production, it seems that the risk of spreading antibiotic resistance in human societies is more related to animals and the veterinary field. In this study, antibiotic resistance, high-level aminoglycoside resistance and frequency of aminoglycoside resistance associated genes amo...

objective: methicillin-resistant staphylococcus aureus is a major cause of nosocomial and community-acquired infections. aminoglycosides are potent bactericidal agents that are often used in combination with either a β-lactam or a glycopeptide, especially in the treatment of staphylococcal endocarditis. the main mechanism of aminoglycoside resistance in staphylococci is drug inactivation by cel...

Background and Aims: Given the importance of aminoglycoside resistance in nosocomial and community infections caused by bacterial pathogenes such as Klebsiella pneumoniae (K. pneumoniae), the aim of this study was to determine the frequency of aac (6')- Ib and aac (3)- IIa, the genes encoding aminoglycoside modifying enzymes involved in aminoglycoside resistance. Material and Methods: A t...

conclusions our results indicate that acetylation genes have an important role in aminoglycoside resistance of the enterococcus isolates from clinical samples. moreover, salmonella strains indicate very low level of aminoglycoside resistance, and aminoglycoside resistance genes were not found in salmonella isolates. these results indicate that other resistance mechanisms, including efflux pumps...

background several studies have shown that species of the genus hyptis, have promising antimicrobial and antifungal effects. objectives identify of chemical constituents of essential oil from leaves of hyptis martiusii and evaluate its effect against bacterial strains by direct and gaseous contact. materials and methods essential oil was extracted from leaves of hyptis martiusii benth using hyd...

conclusions: this study detected multiple drug resistance in pseudomonas aeruginosa including resistance to β-lactams, aminoglycosides, and fluoroquinolones. therefore, identification of drug resistance patterns in p. aeruginosa and detection of pan-resistant producing isolates are of great importance in prevention and control of infections in burn center ward. background: serious infections by...

MexXY is an aminoglycoside-inducible multidrug transporter shown to contribute to intrinsic and acquired aminoglycoside resistance in laboratory isolates of Pseudomonas aeruginosa. To assess its contribution to aminoglycoside resistance in 14 clinical isolates demonstrating a panaminoglycoside resistance phenotype unlikely to be explained solely by aminoglycoside modification, expression of mex...