BACKGROUND Ameloblastic carcinoma secondary type is an extremely rare and aggressive odontogenic neoplasm that exhibits histological features of malignancy in primary and metastatic sites. It arises through carcinomatous de-differentiation of a pre-existing ameloblastoma or odontogenic cyst, typically following repeated treatments and recurrences of the benign precursor neoplasm. Identification...

the ameloblastic carcinoma is a rare malignant counterpart of the ameloblastoma. ameloblastic carcinoma is a malignant lesion with characteristic histologic features and behavior that dictates a more aggressive surgical approach than that of a simple ameloblastoma. however, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. we prese...

ameloblastic carcinoma (ac) is a rare malignant epithelial odontogenic tumor that histologically retains the features of ameloblastic differentiation and exhibits cytological features of malignancy in the primary or recurrent tumor. it may develop within a preexisting ameloblastoma or arise de novo or from an odontogenic cyst. epidemiological evidence shows that human cancer is generally caused...

malignant transformation of ameloblastomas arising from an odontogenic cyst or de novo is wellrecognized. malignancies in ameloblastomas may involve metastasis or a local dysplastic change in the tissue. the latter are classified as ameloblastic carcinomas. a 75-year-old male presented with a mandibular cystic swelling, with no evidence of metastasis. dysplastic ameloblastic cells with spindlec...

The usual treatment for ameloblastic carcinoma is surgical resection. effectiveness of radiotherapy and chemotherapy the disease has not been determined, few effective treatments are available local recurrence distant metastasis. Recently, molecular targeting using BRAFV600E inhibitors attracted interest as a ameloblastoma carcinoma.

AIM To evaluate the use of proliferating cell nuclear antigen index in the different histopathological variants of ameloblastoma, such as the follicular, plexiform, and unicystic types, and in ameloblastic carcinoma by immunohistochemical staining. The proliferating cell nuclear antigen index values of the variants of ameloblastomas and ameloblastic carcinomas are compared in order to determine...

Ameloblastoma is a common and easily diagnosed odontogenic tumor. When present with histologic atypia is crucial because transformation to ameloblastic carcinoma is potentially life-threatening. Ameloblastic carcinoma, the malignant counterpart of the ameloblastoma, a rare entity, is characterized histologically by malignant epithelium in the primary, recurrent, or metastatic deposit. It has a ...

Spindle-cell differentiation in ameloblastic carcinoma is a rare event. Although reported by many authors, it was first described as a separate entity in 1999 by Slater under the heading "low-grade spindle-cell ameloblastic carcinoma." Here, we report a case of low-grade spindle-cell ameloblastic carcinoma arising in pre-existing unicystic ameloblastoma.The patient, a 60-year-old Indian woman, ...

INTRODUCTION Ameloblastoma is a benign odontogenic neoplasm of the jaw, rarely presenting as a malignant tumor. Although it is very important to discriminate ameloblastoma from ameloblastic carcinoma in order to decide the appropriate operative procedure, this is difficult using conventional CT and MRI. CASE DESCRIPTIONS We report a case of maxillar ameloblastoma in a 78-year-old man where FD...

The ameloblastic carcinoma is a rare malignant counterpart of the ameloblastoma. Ameloblastic carcinoma is a malignant lesion with characteristic histologic features and behavior that dictates a more aggressive surgical approach than that of a simple ameloblastoma. However, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. We prese...