Allergic disorders of the ocular surface are primarily characterized as IgE- and/or T-lymphocyte-mediated disorders that affect the cornea, conjunctiva, and eyelid. Approximately 40% of individuals in the developed countries have allergic conjunctivitis, and as such, it is the most common form of ocular allergy. Seasonal allergic conjunctivitis is the most prevalent type of allergic conjunctivi...

PURPOSE To determine the function of γδ T cells in early- and late-phase responses in allergic conjunctivitis. METHODS Wild-type (WT) C57BL/6 and γδ T cell-deficient (TCR-δ(-/-)) mice were immunized intraperitoneally and challenged topically for 7 consecutive days with short ragweed pollen. Natural killer T (NKT) and γδ T cell-double-deficient mice were generated by treating TCR-δ(-/-) mice w...

Purpose We sought to determine whether big data from social media might reveal seasonal trends of conjunctivitis, most forms of which are nonreportable. Methods Social media posts (from Twitter, and from online forums and blogs) were classified by age and by conjunctivitis type (allergic or infectious) using Boolean and machine learning methods. Based on spline smoothing, we estimated the cir...

Allergic conjunctivitis is a common problem that significantly impairs patients' quality of life. Whether air pollution serves as a risk factor for the development of allergic conjunctivitis remains elusive. In this paper, we assess the relationship between air pollutants and weather conditions with outpatient visits for allergic conjunctivitis. By using a time-series analysis based on the larg...

Allergic conjunctivitis caused by sugi pollen is considered to be strictly a "spring disease". However, a recent report indicated that sugi pollen is scattered not only in spring but in all seasons, especially in the autumn. We retrospectively determined the number of patients with allergic conjunctivitis caused by sugi pollen during each month for 3 consecutive years, and also investigated the...

Quercetin offers interesting beneficial options in clinical practice by providing anti-allergic and anti-inflammatory activities. This article reports discusses the effectiveness of oral administration quercetin Phytosome™ adults presenting allergic conjunctivitis. The analysis was conducted evaluating both subjective symptoms reported individuals; objective tear film instability due to conjunc...

We studied 260 children with recurrent wheeze for the presence of allergic rhinitis, allergic conjunctivitis and atopic dermatitis by a questionnaire based survey. We observed that 35% wheezers had allergic rhinitis, 15% had allergic conjunctivitis and 19% had atopic dermatitis. Nasal and eye allergies were often not recognized.

Here, we report on the prevalence of allergic conjunctivitis and positive skin prick test (SPT) results in relation to respiratory allergic conditions among patients with symptoms of allergies at a respiratory outpatient clinic. A questionnaire survey of symptoms (i.e., asthma-like, rhinitis, and conjunctivitis symptoms) involving 1522 patients was carried out. The responses of 1242 patients in...