introduction: the aim of this study was to evaluate the correlation between serum levels of ovarian and gonadotropin hormones, age and number of follicles with follicular alkaline and acid phosphatase activity in infertile women under controlled ovarian hyperstimulation. methods: after collection of follicular fluid and calculation of the number of follicles, the specific activity of alkaline (...

background: the exact pathophysiology of testicular degeneration, following varicocele has not been completely understood yet.   objective: the current study was designed to determine the effect of varicocele on germinal epithelium (ge) cytoplasmic biohistochmical alterations.   materials and methods: to follow-up this study, left varicocele was induced in test groups. non-varicocelized rats we...

specific biological activity when isolated from different species may differ chemically. The haemo. globins are an example of this (Porter & Sanger, 1948), and it is clear that some variation in structure may occur in such a series of compounds without the specific action being greatly modified. From solubility studies, Desreux & Herriott (1939) postulated the existence of at least two componen...

Escherichia coli alkaline phosphatase (AP) is the prototypical two metal ion catalyst with two divalent zinc ions bound approximately 4 A apart in the active site. Studies spanning half a century have elucidated many structural and mechanistic features of this enzyme, rendering it an attractive model for investigating the potent catalytic power of bimetallic centers. Unfortunately, fundamental ...

Administration of anethole at 10 and 50 mg doses caused significant reduction in seminal vesicle weight, RNA and protein concentrations and contents and acid phosphates activity. However, there was significant increase in DNA concentrations and in the activities of alkaline phosphates and lactate dehydrogenase. The effects were more pronounced in the group receiving 50 mg of anethole.

It has been reported previously that polymeric phosphates of phloretin and related compounds are potent inhibitors of several enzymes including alkaline phosphatase and hyaluronidase (Diczfalusy et al. 1953). Preliminary studies suggested that a similar inhibition of acid phosphatases may also take place (Diczfalusy et al. 1953). This paper reports on the kinetics of human seminal acid phosphat...

Phosphorylation of rabbit skeletal muscle glycogen synthase by cyclic AMP-independent synthase kinase 1 results in the incorporation of 4 mol of PO4/subunit. Incubation of the phosphorylated synthase with rabbit muscle phosphoprotein phosphatase brings about the hydrolysis of phosphates from all four major tryptic peptides and an increase in the synthase activity ratio from 0.01 to 0.85. Incuba...