ingested corrosive substances produce different injuries, ranging from minor gastro esophageal burns to death, depending on the agent type, amount, concentration, and duration of substance exposure. the purpose of this study was to investigate the outcomes and different causes of mortality in patients ingesting caustic substances. in a prospective study, between april 1999 and january 2006, a t...

Acquired esophagobronchial fistula (EBF) is a rare condition and its surgical remediation is challenging. Management depends on the cause and degree of the injury. Corrosive substances can be alkaline or acidic in nature. Alkali ingestion commonly causes esophageal injury while acid ingestion most often damages the stomach. However, it is not always clear which gastrointestinal site will be inj...

Over the last ten years disk battery (DB) ingestion have been increasing in children with serious consequences due to the diffusion of lithium battery (LB) that may cause catastrophic damages when lodged in the esophagus. The severity of injury depends on cell type, size, voltage, location and time of contact with the mucosa because electrical generation of hydroxide ions at the negative pole, ...

Serum alkaline phosphatase (SAP) rises after fat ingestion in humans (Langman et al., 1966; Warnock, 1968) and in rats (Jackson, 1952). Recent work in this unit has provided immunological evidence that, in the rat, the fat-induced increase in SAP activity is due predominantly to intestinal alkaline phosphatase (Saini & Posen, 1969). This paper demonstrates, also by an immunological technique, t...

A prospective clinical study was conducted to evaluate whether or not any biochemical predictor of caustic ingestion and complicating esophageal injury exists. Children who were admitted to the hospital within 24 hours following caustic substance ingestion between 1994 and 2000 inclusive were evaluated. The ingested substance and complaints upon admission were noted. Groups were constructed acc...

Ingestion of laundry detergent packets is an important threat to young children. Because of their developmental stage, toddlers are prone to place these small, colorful packets in their mouths. The packets can easily burst, sending a large volume of viscous, alkaline liquid throughout the oropharynx. Ingestion causes major toxic effects, including depression of the central nervous system, metab...

Corrosive esophagitis is characterized by caustic injury due to the ingestion of chemical agents, mainly alkaline substances such as detergents. Esophageal bleeding, perforation, or stricture can be worsened by high-degree corrosive esophagitis. Picosulfate is a commonly used laxative frequently administered for bowel preparation before colonoscopy or colon surgery. Picosulfate powder should be...