addiction to drugs, such as heroin, cocaine and alcohol, exacts great human and financial costs on society. various evidence-based pharmacological and psychosocial interventions are currently used in the treatment of drug addiction but they do not produce adequate therapeutic benefits in every patient. further, barriers such as financial cost, lack of availability, or perceptions of existing tr...

Background: Breastfeeding is the safest and best method for nurturing infant growth and health. While the harmful effects of alcohol during pregnancy are well-established, the consequences of alcohol intake during lactation have been far less examined. The effects of alcohol intake with large amounts noted on the infant include drowsiness, diaphoresis, deep sleep, weakness, decrease in linear g...

Despite common wisdom that reducing alcohol intake will facilitate weight loss, little research has examined whether participants in behavioral weight loss treatments actually decrease their alcohol intake, or whether reduced alcohol intake relates to weight loss outcomes in this context. This study examined the relationship of alcohol use to energy intake excluding alcohol and to weight in 283...

Acute administration of neuropeptide Y (NPY) modulates alcohol intake in genetic and chemical models of high intake, while leaving intake unaffected during 'normal' or baseline conditions. In non-selected, normal rat lines, alcohol consumption can be increased by prolonged exposure to alcohol, and it is unclear what effect a constitutive increase in NPY function will have on alcohol intake. The...

There are no data concerning a relationship between alcohol and bone status from a large-scale community-based study of elderly Japanese men. The baseline survey for the Fujiwara-kyo Osteoporosis Risk in Men Study was performed in 2174 male participants during the period from 2007 to 2008 in Nara Prefecture, Japan. Among them 1665 fitted the following inclusion criteria: (a) age ≥65years, (b) n...

BACKGROUND The prevalence of alcohol intake is increasing among women in some populations. Alcohol consumption plays an important role in the risk of major cardiovascular outcomes and total mortality. Here, we conducted a meta-analysis to estimate the association between alcohol intake and major cardiovascular outcomes or total mortality in women compared with men. METHODS We searched the Pub...

1/09 8 Alcohol forms a significant component of the diet in many countries. Nationwide studies indicate an average per capita consumption of about 10–30 gram per day or about 3–9% of the daily energy intake. In the United States, the per capita consumption of alcohol shifted from 1.3% of daily energy intake in 1965 to 4.5% of daily energy intake in 2002 (1). The efficiency with which alcohol en...

Recent recommendations in regard to the level of alcohol intake have mainly been based on epidemiologic studies which relied on self-reported amounts of alcohol consumed. Therefore, it is important to be aware of the quality of self-reported measures of alcohol intake. Alcohol intake assessment methods were reviewed with respect to their capacity to rank individuals according to alcohol intake ...

BACKGROUND Alcohol intake has been shown to be associated with an increased risk for breast cancer. In the analysis of longitudinal prospective cohort studies, however, the analysis of repeated measurements of alcohol intake might not be straightforward. METHODS In this analysis of the Copenhagen City Heart Study, in which alcohol intake was measured four times, 9318 Danish women with no prev...

Experimental animal models are critical for understanding the genetic, environmental and neurobiological underpinnings of alcohol use disorders. Limited studies investigate alcohol-induced effects on behavior using free-choice paradigms. The aims of the present experiment were to study voluntary alcohol intake using a modified intermittent access paradigm, investigate the effects of voluntary a...