Objective: In patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. We designed a study for comparing the level of Ox-LDL in diabetic patients with Macro-albuminuria, Micro-albuminuria, versus Normo-albuminuric. Materials and Methods: One hundred and thirty five patients with type 2 dia...

Objective: Oxidative stress plays an important role in the onset and progression of diabetic nephropathy. So antioxidant agents may be one of the key treatment strategies for prevention of diabetic nephropathy progression .The aim of this study was to determine the effect of selenium (Se) on micro-albuminuria in type 2 diabetic (T2DM) patients. Materials and Methods: This study was a clinical ...

objective: in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. we designed a study for comparing the level of ox-ldl in diabetic patients with macro-albuminuria, micro-albuminuria, versus normo-albuminuric. materials and methods: one hundred and thirty five patients with type 2 diabet...

conclusions our study obtained some evidences on the association of micro albuminuria with diastolic dysfunction in obese normotensive no diabetic individuals. nonetheless, more assessment is necessary for obtaining a causal relationship between micro albuminuria and diastolic dysfunction. background recently, an association between impaired diastolic function and increased urinary albumin excr...

background impaired fasting glucose (ifg), and impaired glucose tolerance (igt) are two prediabetes conditions which have some correlation with macrovascular disorders. the risk of microvascular complications in these groups is not clear. objectives the prevalence of albuminuria in subjects with ifg and igt was evaluated in the present study. patients and methods in this study three groups of s...

Background: Early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. Angiotensin converting enzyme inhibitors (ACEIs) and antagonists of angiotensin II receptors type I (ARBs) are currently used as first-line treatment for albuminuria in these patients. The present study was conducted to assess the efficacy of addition of spi...

Background: Type 2 diabetes mellitus (T2D) patients with albuminuria have coronary microvascular dysfunction (CMD). Fractional flow reserve assessed by computed tomography angiography (FFRct) is dependent on the structure and function of microcirculation likely influenced CMD. We aimed to evaluate if asymptomatic T2D who had no significant artery stenosis but been diagnosed lower value nadir FF...

Albuminuria reduction could be renoprotective in hypertensive patients with diabetic nephropathy. However, the current use of renin-angiotensin-system intervention is targeted to BP only. Therefore, this study investigated the adequacy of this approach in 1428 patients with hypertension and diabetic nephropathy from the placebo-controlled Reduction of Endpoints in NIDDM with the Angiotensin II ...

OBJECTIVES We sought to compare systolic and diastolic function in American Indians with diabetes mellitus (DM) based on albuminuria status. BACKGROUND Albuminuria has been shown to predict cardiovascular disease (CVD) in populations with DM. However, the mechanism of the association of albuminuria and CVD is unclear. METHODS We compared echo-derived indices of left ventricular (LV) systoli...