BACKGROUND Cis-planaramineplatinum(II) complexes like their trans isomers are often found to be active against cancer cell lines. The present study deals with the synthesis, characterization and determination of activity of new cis-planaramineplatinum(II) complexes. RESULTS Two cis-planaramineplatinum(II) complexes: cis-(3-hydroxypyridine)(ammine)dichloroplatinum(II) (code named AH3) and cis-...

We examined the incidence of amantadine-resistant influenza AH3 viruses isolated in Nara Prefecture during the 2005-06 winter season. The genetic analyses of the M2 ion channel protein were conducted using reverse transcriptase PCR and direct sequencing. Thirteen out of 18 (72.2%) strains were identified as amantadine-resistant, and this incidence was remarkably higher than those previously rec...

Molecular tumour targeting has significantly improved anti-cancer protocols. Still, the addition of molecular targeting to the treatment regime has not led to a curative breakthrough. Combined mammalian target of Rapamycin (mTOR) and histone deacetylase (HDAC) inhibition has been shown not only to enhance anti-tumour potential, but also to prevent resistance development seen under mono-drug the...

*Corresponding author: Mailing address: Department of Microbiology and Zoology, Aichi Prefectural Institute of Public Health, Nagare 7-6, Tsujimachi, Kita-ku, Nagoya 462-8576, Japan. Tel: +81-52-910-5674, Fax: +81-52-913-3641, E-mail: mami_hata@ pref.aichi.lg.jp Since the pandemic of 1968, the H3N2 subtype of influenza A virus (AH3) continues to circulate and has caused significant morbidity an...

*Corresponding author: Mailing address: Sapporo City Institute of Public Health, 9-1-5-22 Kikusui, Shiroishi-ku, Sapporo 003-8505, Japan. Tel: +81-11-841-8875, Fax: +81-11-841-9509, E-mail: [email protected] Influenza in the 2005/06 season (September 2005 August 2006) in Sapporo, Japan, was characterized by mixed epidemics of the type AH3, AH1 and B viruses, and the predominant v...

*Corresponding author: Mailing address: Virology and Bacteriology Division, Nara Prefectural Institute for Hygiene and Environment, Ohmori-cho, Nara 630-8131, Japan. Tel: +81-74220-2887, Fax: +81-742-27-0634, E-mail: [email protected]. nara.jp An influenza outbreak occurred in summer, a non-epidemic season, in a hospital in the northern area of Nara Prefecture, Japan. The outbreak occurred in...

Results Using molecular diagnostic methods (PLEX-ID, Multiplex PCR) we identified, in the respiratory secretions and in the CSF: H1N1 influenza virus (2009), influenza AH3 virus, influenza B virus, coronavirus and adenovirus. The most severe forms of the disease were caused by the influenza virus H1N1. There were 2 cases of encephalitis admitted with this etiology, one of which had a fatal outc...

calcium aluminates (ca) are the most important hydraulically setting cements used for preparing refractory castables, because they develop high strength at very early ages after placements.  the anhydrous phases of this kind of cements are ca, ca2 and traces of c12a7 and alpha-alumina. the major hydraulic phase in all of the ca cements including ciment fondue is ca. once hydrated, it starts to ...

Multiparameter radar measurements were made during a heavy rainfall event accompanied by hail in Colorado. Rainfall rates R and accumulation for this event were estimated using S-band specific differential phase KDP, reflectivity factor ZH, and X-band specific attenuation AH3. These estimates were compared with measurements from a ground-based rain gauge. Both R–KDP and R–AH3 relations were in ...

Achieving and controlling the desired strength build-up is important for 3D concrete printing. In this paper, we investigate possibility of using calcium aluminate cement (CAC) as an accelerator Ordinary Portland Cement (OPC) extrusion Both ternary binary systems were studied whereby former, third component was a sulfate source (C$). Experiments are conducted on mixes both in presence absence r...