1. The sera of 80 per cent of the rabbits intravenously inoculated with fixed amounts of heat-killed pneumococci contained agglutinins and all showed protective antibodies. 2. The sera of 60 per cent of the intraperitoneally inoculated rabbits contained agglutinins and all showed protective antibodies. 3. The sera of 33 per cent of the intramuscularly inoculated rabbits contained agglutinins an...

Fertilization in Chlamydomonas reinhardtii is initiated when gametes of opposite mating types adhere to each other via adhesion molecules (agglutinins) on their flagella. Adhesion leads to loss of active agglutinins from the flagella and recruitment of new agglutinins from a pool associated with the cell body. We have been interested in determining the precise cellular location of the pool and ...

The agglutinins present in the seeds of Abrus precatorius and Ricinus communis have been separated from the toxins, abrin and ricin, and extensively purified. The procedure involves ion exchange chromatography on DEAEand CMcellulose columns, affinity chromatography on Sepharose 4B columns, and sucrose gradient centrifugation. The purified agglutinins which possessed almost no toxic activity wer...

The agglutinins towards Bacillus abortus found in the blood serum of new-born calves are obtained from the mother through the colostrum. Calves at birth, unfed, are without agglutinins. The problem of the production of agglutinins by the fetus in whose tissues Bacillus abortus has multiplied and which is subsequently expelled prematurely is not touched by these observations.

1. The absorption of typhus sera (human or antityphus horse serum) with Proteus X-19 removes only the Proteus agglutinins, leaving the Rickettsia agglutinins intact. 2. The absorption of typhus sera with Mexican Rickettsiae removes the agglutinins for both the Rickettsia and Proteus X-19. 3. While normal or formalinized Rickettsiae are not agglutinated by anti-Proteus serum, these organisms-whe...

1. Agglutinins are present in the blood of patients suffering from lobar pneumonia during some stage of the disease in a large percentage (73.8 per cent.) of the cases due to pneumococci belonging in groups I, II, and IV. 2. In most very severe and fatal cases agglutinins cannot be demonstrated, and it is probable that their absence during the later days of the disease may have unfavorable prog...

Two serologically distinct antibodies directed against different antigenic sites on the Group A carbohydrate were detected in human sera by agglutination techniques. Agglutinins with A-variant specificity were demonstrable by the direct agglutination of purified A-variant cell walls, whereas indirect Coombs-type agglutinins with Group A specificity were demonstrable with Group A cell walls. Sel...

Agglutinins for the meningococcus were not found in the spinal fluid of normal monkeys which had received antimeningococcic serum intravenously. The intraspinal injection of isotonic salt solution, normal horse serum, or a culture of living meningococci allows agglutinins for the meningococcus to pass from the blood to the spinal fluid of the passively immunized monkey; and the rate of the pass...