one of the most serious kinds of hepatitis is hepatitis b. this condition is more common than aids, and is 100 time more contagious. in iran the most common cause of acute and chronic hepatitis, liver cirrhosis, and also hepatocellar carcinoma in adults, is hepatitis b. more than two billion people are infected and more than 350 million of individuals are carriers of this virus in the entire wo...

Hepatitis B core antigen (HBc Ag) and hepatitis B surface antigen (HBs Ag) were detected in the liver tissue of a patient with chronic aggressive hepatitis by the immunofluorescent complement technique. The presence of anti-HBc was examined by the same method in 67 human sera previously tested for HBs Ag, anti-HBs and s-GPT levels. HBc Ag was localized mainly in the nucleus and sometimes in the...

In chronic hepatitis B (CHB), the persistence of hepatitis B surface antigen (HBs Ag) is sometimes associated with antibodies (Ab) to HBs (anti-HBs). To assess the hypothesis of the selection of HBs Ag immune escape variants in CHB patients, the variability of the HBV S gene was determined for patients persistently carrying both HBs Ag and anti-HBs antibodies and patients solely positive for HB...

in order to determine the prevalence, incidence and odd ratio of hbv, 681 serum samples were collected from 54 laboratory personnel in tehran in both private and governmental sectors. the samples were tested for hbsag and ab using elisa technique. the results showed that the prevalence of hbsag and ab among clinical laboratory personnel was 2.3 and 20 percent respectively. the prevalence of hbs...

Comparative biophysical and biochemical analyses were performed on purified preparations of hepatitis B antigen (HBs Ag) subtypes adw and ayw, including isoelectric pH evaluations, analysis of the different morphological forms, molecular weight determinations, and analysis of the polypeptides by polyacrylamide gel electrophoresis, Both HBs Ag-positive plasma and purified HBs Ag were analyzed by...

The first universal hepatitis B vaccination program for newborns in the world was launched in Taiwan in July 1984. Most studies on the effectiveness of hepatitis B vaccination focused on the seroprevalence of HBs Ag among children under 14 years old. Only few studies focused on the seropositivity of anti-HBs among adolescents aged 15-18 years old. The present study aimed to evaluate the impact ...

Entecavir requires long-term administration. Pegylated interferon (PEG-IFN) therapy leads to significant reduction of hepatitis B surface antigen (HBs Ag) levels. This study aimed to assess the safety and efficacy of adding PEG-IFN-α-2a to entecavir toward cessation of entecavir. A total of 23 patients treated with entecavir underwent add-on PEG-IFN-α-2a therapy (90 μg per week) for 48 weeks. V...

introduction: viral hepatitis is one of the causes of premature death in world peoples, according to who reports, five percentage of people are carrier, lethal from this disease is 1%, therefore about 1-1.5 million people each year die from complications of this disease. this disease varies from an acute to chronic illness. the aim of this study was to determine the level of anti-hbs ag (hepati...