نتایج جستجو برای: adventitious agents
تعداد نتایج: 362471 فیلتر نتایج به سال:
Background and Aims: Adventitious agents, especially viral agents are among the most important concerns in viral vaccines. Viral contamination of biological products may arise from the original source of the reagents such as, serum, trypsin, animal or human derived media components or cell culture and working seed or cross contamination of vaccine during production. In this study, adventitious ...
background and aims: adventitious agents, especially viral agents are among the most important concerns in viral vaccines. viral contamination of biological products may arise from the original source of the reagents such as, serum, trypsin, animal or human derived media components or cell culture and working seed or cross contamination of vaccine during production. in this study, adventitious ...
Vaccines are one of the most effective public health medicinal products with an excellent safety record. As vaccines are produced using biological materials, there is a need to safeguard against potential contamination with adventitious agents. Adventitious agents could be inadvertently introduced into a vaccine through starting materials used for production. Therefore, extensive testing has be...
Emerging Infectious Diseases Vol. 7, No. 3 Supplement, June 2001 562 A discussion of adventitious agents and vaccines is pertinent in the context of emerging infectious diseases. Many novel vaccines are produced in animal cell substrates, and emerging infectious diseases may theoretically be transmitted from animals to humans through these vaccines. The challenge of identifying potential advent...
The preparation of virus vaccines in monkey kidney tissue cultures may be complicated by the presence of adventitious agents in tissues of some of the animals (J. L. Bittle et al., J. Infect. Diseases 116:215, 1966). The problem is compounded when fluids derived from the cell cultures of several monkeys are pooled, since one contaminated animal would spoil the entire lot. This situation may be ...
Since the earliest days of biological product manufacture, there have been a number of instances where laboratory studies provided evidence for the presence of adventitious agents in a marketed product. Lessons learned from such events can be used to strengthen regulatory preparedness for the future. We have therefore selected four instances where an adventitious agent, or a signal suggesting t...
Mondia whitei (Hook.f.) Skeels is an important endangered medicinal and commercial plant in South Africa. In vitro propagation systems are required for biomass production and bioactivity analysis to supplement wild resources/stocks. Adventitious roots from somatic embryogenic explants using suspension culture and ex vitro-grown plants produced via somatic embryogenesis were established using di...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید