the ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals areconverted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead thestructural changing in hemoglobin. in the present work, aggregation of the purified hemoglobinin adult (hba) and in fetus or newborn (hbf) in the presence of nitrite ions were studied.hemoglobin aggregation was perform...

The ingested nitrates sourced from tap water, food, chemicals and pharmaceuticals areconverted to nitrites in the body surfaces by bacteria and then, the nitrite ions can lead thestructural changing in hemoglobin. In the present work, aggregation of the purified hemoglobinin adult (HbA) and in fetus or newborn (HbF) in the presence of nitrite ions were studied.Hemoglobin aggregation was perform...

in 1979, a community health survey for the purpose of establishing population babe. services were conducted in the villages of region of isfahan with a population of about 10,000. the target group involved males and females with in the age group of more than one year old. the population under study, 617 males and 565 females who were selected by household random sampling, where examined for the...

ETICULOCYTES of several species have been shown to accumulate amino acids, and incorporate them into hemoglobin.12 While the ratio of the concentration of certain amino acids in mature human red cells to the plasma concentrations of the same amino acids has been studied,1 there has been no study of this ratio in human reticulocytes. Because of the presence of large amounts of fetal hemoglobin i...

SUMMARY A 'switchover' from synthesis of predominantly embryonic hemoglobin to synthesis of predominantly adult hemoglobin occurs during differentiation of the house sparrow. This 'switchover' is demonstrated by a change in electrophoretic pattern generally comparable with that of the chicken, slightly different from those of the duck and man, and, perhaps, dissimilar to that of the red-wing bl...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 1379 in developing humans: the embryonic, Gower-I, Gower-II, Portland, fetal hemoglobin (HbF) and normal adult hemoglobin (HbA and HbA2). HbF is the primary hemoglobin found in the fetus. It has a higher affinity for oxygen than adult hemoglobin, thus increasing the efficiency of oxygen transfer to the fetus. The relative quantities of HbF rapidly decr...

What causes the gradual decrease of fetal hemoglobin in the normal maturing infant, or the persistence of fetal hemoglobin in the blood of adults with certain congenital anemias, especially thalassemia, is not known. The production of fetal hemoglobin is evidently determined by genes nonallelic with those regulating adult hemoglobin formation (1). The fact that all red cells can be sickled in s...

Studies were carried out during the neonatal period in three infants with D1 trisomy syndrome to measure the proportion of fetal and adult hemoglobin being synthesized. These values were compared on the one hand to those previously reported from samples obtained from cord blood of normal newborn infants ranging from 25 to 43 wk gestation, and on the other hand to those values determined in crit...