adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations. insufficient glucocorticoid doses result in adrenal crisis and must be treated with intravenous hydrocortisone. the patient was known with adrenal insufficiency and was treated optimally with fludrocortisone...

allgrove syndrome also known as triple-a syndrome is an autosomal recessive disorder characterized by alacremia, achalasia and acth-resistant adrenal insufficiency. although this syndrome is rare, herein we report four cases with different clinical manifestations. they were referred to the gastrointestinal ward during a one year period with complaints of vomiting and dysphagia. the diagnosis of...

introduction the current study introduces a case with adrenal insufficiency that was suspected to have congenital adrenal hypoplasia because of undescended testis and failure to thrive due to muscle involvement. case presentation the patient was a 34-month-old boy who had loss of consciousness, hypotension, hypoglycemia, hyponatremia and hyperkalemia with severe failure to thrive, hyper pigment...

primary adrenal insufficiency (addison’s disease) is due to adrenocortical disease. this study is about a 40 year old man who had been referred to a hematologist who assessed him for anemia. he  had been affected by a periodic paresthesia one month prior to his visit to the physician. according to the clinical presentation, macrocytic anemia and hypersegmentation of pmn in pbs, bma/b was perfor...

Adrenal insufficiency is characterized by decreased production of glucocorticoids from adrenal cortex, either due to a primary or secondary pituitary etiology. Neuropsychiatric symptoms and signs could be the first presenting only presentation are relatively less explored in patients with understood. Patients chronic psychiatric symptoms, namely depression anxiety should evaluated for associati...

background: acute intoxication with alp is extremely lethal. the present study was conducted to determine the range of serum cortisol levels in alp poisoning and its correlation with patient outcome. methods: this study was carried out on patients who were intoxicated with alp. their demographic data and pertinent findings in their history and physical examination were recorded at the time of a...

conclusions whenever a cushingoid appearance is accompanied by adrenal insufficiency, the exogenous use of steroids, especially topical creams, should be explored. hypertension may persist even after cessation of use and may result in life threatening complications. case presentation the present report describes the cases of three children and a 25-year-old man who presented with clinical featu...

Adrenal insufficiency can often manifest with nonspecific complaints. Primary adrenal lymphoma is a rare cause of adrenal insufficiency. We present the case of a 55-year-old female who presented with nonspecific complaints of abdominal pain, pallor and weight loss and was found to have primary adrenal lymphoma. The case highlights the need to expeditiously initiate steroid replacement in patien...

BACKGROUND Auto-immune adrenal insufficiency is a potentially fatal disorder. Young women with spontaneous premature ovarian failure (POF) are at increased risk of developing this condition. METHODS We further characterized auto-immune adrenal insufficiency in this population by conducting an in-depth cross-sectional evaluation of adrenal function in a series of 123 women. RESULTS We uncove...