نتایج جستجو برای: adli
تعداد نتایج: 1054 فیلتر نتایج به سال:
BACKGROUND Anti-tuberculosis (anti-TB) drug-induced liver injury (ADLI) is one of the most common adverse effects associated with TB treatment. Cytochrome P450 (CYP) 1A1 and glutathione S-transferase (GST) P1 are important phase I/II metabolizing enzymes involved in drug metabolism and detoxification. Genetic polymorphism and CpG island methylation have been reported as factors influencing the ...
This paper makes use of a 1997 computable general equilibrium (CGE) model to analyse three potential strategies that Mozambique can pursue unilaterally with a view to initiating a sustainable development process. They include (i) an agriculture-first strategy, (ii) an agricultural-development led industrialization (ADLI) strategy, and (iii) a primary-sector export-oriented strategy. The ADLI st...
Donor lymphocyte infusions (DLIs) induce potent graft versus tumor (GVT) effects for relapsed chronic myelogenous leukemia (CML) after allogeneic stem cell transplantation (SCT) but are disappointing for other diseases. Disease resistance can occur if donor T cells are not appropriately activated in vivo. Ex vivo T-cell activation might overcome diseaseinduced anergy and augment GVT activity. W...
Donor lymphocyte infusions (DLIs) induce potent graft versus tumor (GVT) effects for relapsed chronic myelogenous leukemia (CML) after allogeneic stem cell transplantation (SCT) but are disappointing for other diseases. Disease resistance can occur if donor T cells are not appropriately activated in vivo. Ex vivo T-cell activation might overcome disease-induced anergy and augment GVT activity. ...
This study investigated the role of CpG island methylation of the CYP2E1 and CYP2D6 genes in liver injury induced by anti-TB drugs from an epigenetic perspective in a Chinese cohort. A 1:1 matched nested case-control study design was applied. Pulmonary tuberculosis (TB) patients, who underwent standard anti-TB therapy and developed liver injury were defined as cases, while those who did not dev...
Liver injury is a major hindrance to the treatment of tuberculosis (TB) patients due to the primary side effects associated with anti-TB drugs. Several investigations have identified sensitive biomarkers for the early diagnosis of anti-TB drug-induced liver injury (ADLI), including the use of microRNAs (miRNAs/miRs). However, the association between miR-122/155 and ADLI remains unknown. Thus, t...
Anuradha Illendula , Jane Gilmour , Jolanta Grembecka , Venkata Sesha Srimath Tirumala , Adam Boulton , Aravinda Kuntimaddi , Charles Schmidt , Lixin Wang , John A. Pulikkan , Hongliang Zong , Mahmut Parlak , Cem Kuscu , Anna Pickin , Yunpeng Zhou , Yan Gao , Lauren Mishra , Mazhar Adli , Lucio H. Castilla , Roger A. Rajewski , Kevin A. Janes , Monica L. Guzman , Constanze Bonifer , John H. Bus...
OBJECTIVES Patients with cognitive impairment may have difficulty reporting their functional and cognitive abilities, which are important clinical outcomes. Health care proxies may be able to corroborate patient self-reports. Several studies reported discrepancy between patient and proxy ratings, though the literature is sparse on changes over time of these ratings. Our goals in this 12-month s...
W. An, M. Zhou, N. Vafaei-Najafabadi, K.A. Marsh, C. E. Clayton, C. Joshi, W. B. Mori, W. Lu, E. Adli, S. Corde, M. Litos, S. Li, S. Gessner, J. Frederico, M. J. Hogan, D. Walz, J. England, J. P. Delahaye, and P. Muggli Department of Electrical Engineering, University of California Los Angeles, Los Angeles, California 90095, USA Department of Physics and Astronomy, University of California Los ...
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