objective: administration of amoxicillin and metronidazole along with scaling and root planning (srp) is an effective adjunctive therapy for chronic periodontitis. studies have shown that administration of azithromycin is also effective for treatment of chronic periodontitis. this study aimed to compare the effect of short-term and long-term azithromycin regimen with amoxicillin and metronidazo...

BACKGROUND Plasminogen deficiency is a rare autosomal recessive disease, which is associated with aggressive periodontitis and gingival enlargement. Previously described treatments of plasminogen deficiency associated periodontitis have shown limited success. This is the first case report indicating a successful therapy approach consisting of a non-surgical supra- and subgingival debridement in...

introduction: the optimum removal of bacteria and their toxins from periodontal pockets is not always obtained by conventional mechanical debridement. adjunctive therapies may improve tissue healing through detoxification and bactericidal effects. the purpose of the present study was to evaluate the impact of adjunctive laser therapy (lt) and photodynamic therapy (pdt) on patients with chronic ...

Background. Melatonin can eliminate free radicals and this function can be intensified byvitamin C. Melatonin and vitamin C can have synergic antioxidant effects. The aim of thisstudy was to investigate the effects of adjunctive use of melatonin and vitamin C in the non-surgical treatment of chronic periodontitis. Methods. Sixty subjects with chronic periodontitis were included in this study an...

An increasing number of patients have become aware of the detrimental effects of periodontal disease and tooth-loss and they seek periodontal care. The cornerstone of management of chronic periodontitis is the non-surgical periodontal treatment. The primary goal of periodontal therapy is to preserve the natural dentition by achieving and maintaining a healthy functional periodontium. Many adjun...

AIM We investigated the long-term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented by systemic antibiotics, although its impact on the course of disease is still unclear. MATERIAL & METHODS This prospective, randomized, double-blind, placebo-controlled multi-centre trial comprising patients suffering from moderate to ...

Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by nonsurgical mechanical debridement and regular periodontal maintenance care. Periodontal surgery...

OBJECTIVES The aim was to answer three relevant questions: can systemic antimicrobials be efficacious if the biofilm is not disrupted? Can the type of debridement of the subgingival biofilm impact upon the clinical outcomes of the adjunctive antimicrobial therapy? Is the efficacy of the adjunctive systemic antimicrobial therapy dependent on the quality of the debridement of the subgingival biof...