نتایج جستجو برای: adipo r2

تعداد نتایج: 30263  

Journal: :The Journal of clinical endocrinology and metabolism 2005
J Eduardo Caminos Rubén Nogueiras Rosalía Gallego Susana Bravo Sulay Tovar Tomás García-Caballero Felipe F Casanueva Carlos Diéguez

CONTEXT Adiponectin is an adipocyte hormone involved in glucose and lipid metabolism. Recently, two receptors of this protein, called adiponectin receptor 1 (Adipo-R1) and Adipo-R2, have been cloned. OBJECTIVE The aim of this study was to examine whether adiponectin and its receptors are expressed in human and rat placentas and to evaluate the regulation of these factors by gestational age an...

Journal: :Asian Pacific Journal of Cancer Prevention 2015

2017
Jennifer L. Bradley Tsuyoshi Tanabe Erika Tokita Shuichi Kawano Isao Suzaki Kosaku Komiya Tomohiro Akaba

OBESITY AND ASTHMA: ADIPONECTIN RECEPTOR 1 (ADIPO R1) AND ADIPONECTIN RECEPTOR 2 (ADIPO R2) ARE EXPRESSED BY NORMAL HUMAN BRONCHIAL EPITHELIAL (NHBE) CELLS AT AIR-LIQUID INTERFACE (ALI) AND EXPRESSION CHANGES WITH IL-13 STIMULATION By Jennifer Bradley, M.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science, at Virginia Commonwealth University. Vir...

2013
Somayeh Bohlouli Mozafar Khazaei Masoud Teshfam Hosein Hassanpour

BACKGROUND Adiponectin is one of the most important adipokines secreted from fatty tissue that has a direct inhibitory effect on the development of cancer cells. Adiponectin plays an important role in human reproduction system and fertility of women. Adiponectin concentration decreases in women with endometriosis and endometrial cancer. The aim of the present study was to investigate the effect...

Journal: :International journal of molecular medicine 2006
Gian Paolo Rossi Daniele Sticchi Luisa Giuliani Paolo Bernante Silvia Zavattiero Achille C Pessina Gastone G Nussdorfer

Adiponectin is an adipocyte-derived circulating peptide that plays an important role in adipose tissue metabolism, insulin sensitivity and cardiovascular disease. The adrenal gland, by secreting glucorticoid and mineralocorticoid hormones, intervenes in cardiovascular and glucose metabolism regulation and is surrounded by adipose tissue. Hence, we investigated the hypothesis that adiponectin re...

2015
Shubhankar Suman Bhaskar V. S. Kallakury Albert J. Fornace Kamal Datta

Ionizing radiation is a known risk factor for gastrointestinal (GI) pathologies including cancer. Hormones and related signaling crosstalk, which could contribute to radiation-induced persistent pathophysiologic changes in the small intestine and colon, remain to be explored. The current study assessed perturbation of GI homeostasis-related hormones and signaling pathways at the systemic as wel...

Journal: :PeerJ 2015
Alison Hall Martin Leuwer Paul Trayhurn Ingeborg D Welters

Background. Adipose tissue contributes to the inflammatory response through production of cytokines, recruitment of macrophages and modulation of the adiponectin system. Previous studies have identified a down-regulation of adiponectin in pathologies characterised by acute (sepsis and endotoxaemia) and chronic inflammation (obesity and type-II diabetes mellitus). In this study, we investigated ...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2014
David I Kasahara Hye Y Kim Joel A Mathews Norah G Verbout Alison S Williams Allison P Wurmbrand Fernanda M C Ninin Felippe L Neto Leandro A P Benedito Christopher Hug Dale T Umetsu Stephanie A Shore

Adiponectin is an adipose-derived hormone with anti-inflammatory activity. Following subacute ozone exposure (0.3 ppm for 24-72 h), neutrophilic inflammation and IL-6 are augmented in adiponectin-deficient (Adipo(-/-)) mice. The IL-17/granulocyte colony-stimulating factor (G-CSF) axis is required for this increased neutrophilia. We hypothesized that elevated IL-6 in Adipo(-/-) mice contributes ...

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