Objective(s) Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial and community infections. Biofilm formation, mediated by a polysaccharide intercellular adhesin (PIA) and encoded by the ica operon, is considered to be an important virulence factor in both S. epidermidis and S. aureus. However, the clinical impact of the ica locus and PIA production is less w...

objective(s) methicillin-resistant staphylococcus aureus (mrsa) is an important cause of nosocomial and community infections. biofilm formation, mediated by a polysaccharide intercellular adhesin (pia) and encoded by the ica operon, is considered to be an important virulence factor in both s. epidermidis and s. aureus. however, the clinical impact of the ica locus and pia production is less wel...

UNLABELLED Biofilm formation by Candida albicans on medically implanted devices poses a significant clinical challenge. Here, we compared biofilm-associated gene expression in two clinical C. albicans isolates, SC5314 and WO-1, to identify shared gene regulatory responses that may be functionally relevant. Among the 62 genes most highly expressed in biofilms relative to planktonic (suspension-g...

Candida albicans is a major human fungal pathogen. One of the important features of C. albicans pathogenicity is the ability to form biofilms on mucosal surfaces and indwelling medical devices. Biofilm formation involves complex processes in C. albicans, including cell adhesion, filamentous growth, extracellular matrix secretion and cell dispersion. In this work, we characterized the role of th...

The Candida albicans RHR2 gene, which specifies a glycerol biosynthetic enzyme, is required for biofilm formation in vitro and in vivo. Prior studies indicate that RHR2 is ultimately required for expression of adhesin genes, such as ALS1. In fact, RHR2 is unnecessary for biofilm formation when ALS1 is overexpressed from an RHR2-independent promoter. Here, we describe two additional biological p...

Goat milk has become a popular item of human consumption due to its originality. Enterococci are ubiquitous bacteria, and they can also be found in traditional dairy products. This study focuses on the safety enterococci from Slovak raw goat their susceptibility lantibiotic bacteriocins durancin ED26E/7, which not previously been studied. Biofilm formation ability enterococci, virulence factor ...

Background: There are scarce reports about the association of Klebsiella oxytoca ( K. ) with urinary tract infection (UTI) in children. We aimed to evaluate prevalence fimA, mrkA, matB and pilQ adhesins genes extended-spectrum beta-lactamase (ESBL) blaCTX-M, blaTEM blaSHV by polymerase chain reaction (PCR) study biofilm formation antibiotics resistance from children UTI. Methods: This was a ret...

Staphylococcus aureus (S. aureus) is the most common pathogen causing infections from skin to systemic infections. The success of S. can partially be attributed its antibiotic resistance and ability form biofilm. An increasing prevalence methicillin-resistant (MRSA) becomes a global public health problem in recent decades. Here, effects tea catechin extracts on growth biofilm formation three MR...

Objective(s): The present study investigated the prevalence of genes encoding for exotoxins, adhesion and biofilm factors in Staphylococcus aureus isolates obtained from samples in a referral burn hospital in Tehran, Iran.Materials and Methods: S. aureus isolates obtained from patients, personnel and surfaces in the wards of a burn hospi...

An increase in the antibiotic resistance among Enterococcus faecium strains has been observed worldwide. Moreover, this bacteria has the ability to produce several virulence factors and to form biofilm that plays an important role in human infections. This study was designed to compare the antibiotic resistance and the prevalence of genes encoding surface protein (esp), aggregation substance (a...