We present a series of sterically demanding Eu( iii ) complexes and identify the optimal position peripheral phenylboronic acid to achieve multisite recognition AMP (adenosine monophosphate) in aqueous solution.

Adenosine-3',5'-cyclic monophosphate was shown to be the compound found in Escherichia coli responsible for the attraction of the amoebae of the cellular slime mold Dictyostelium discoideum. A number of other nucleotides were tested and the following were active: tubercidin-3',5'-cyclic monophosphate, N(6)-2'-O-dibutyryl-adenosine-3',5'-cyclic monophosphate, 5'-methylene adenosine-3',5'-cyclic ...

A styrylpyridine-containing cyclophane with diethylenetriamine linkers is presented as a host system whose association representative nucleotides was examined photometric and fluorimetric titrations. The spectrometric titrations revealed the formation of 1:1 complexes log Kb values in range 2.3–3.2 for pyrimidine TMP (thymidine monophosphate), TTP triphosphate) CMP (cytidine monophosphate) 3.8–...

This study examined the effects of long-term frozen storage (-20 °C for 5 months) of free amino acids (FAAs) and nucleotide-related compounds (NRCs) in muscle and hepatopancreas of the coconut crab Birgus latro. Although long-term frozen storage had little effect on FAA composition in muscle, the amounts of several FAAs increased in the hepatopancreas that may be the result of protein decom...

Increases in cyclic adenosine monophosphate and cyclic guanosine monophosphate content accompany relaxation of isolated strips of opossum and canine lower oesophageal sphincter muscle. The aim of this investigation was to characterise these responses in isolated muscle from the human lower oesophageal sphincter. Electrical stimulation of enteric neurons produced a frequency dependent relaxation...

The mechanisms by which adenosine triphosphate, thrombin, and trypsin cause relaxation of vascular smooth muscle were investigated. Relaxation of the rat thoracic aorta with adenosine triphosphate, thrombin, and/or trypsin was associated with increased levels of cyclic guanosine monophosphate in both time- and concentration-dependent manners. Thrombin and trypsin did not alter cyclic adenosine ...

S-Adenosylhomocysteine (SAH) hydrolase was purified 25-fold from bakers' yeast by chemical methods and column chromatography. The purified enzyme could readily synthesize SAH from adenosine and homocysteine, but could hydrolyze only negligible amounts of SAH. The purified enzyme showed no activity towards S-adenosylmethionine, methylthioadenosine, or adenosine. Several nucleotides, sulfhydryl c...

Fetal rat calvaria were incubated in Krebs-Ringer-bicarbonate medium, containing glucose (2 mg per ml) and bovine serum albumin (1 mg per ml). Incubation in a medium with 0.3 or 0.6 mM dibutyryl adenosine 3’,5’monophosphate (DBcAMP) for 15 min caused a Zto S-fold increase in the tissue concentration of adenosine 3’,5’monophosphate (3’,5’-AMP). This rise could not be explained by degradation of ...