background: toxoplasmosis is well known as an important infection in pregnant women. although many serologic methods are available, diagnosis of early toxoplasmosis may be extremely difficult. objective: to detect the toxoplasma igg antibodies developed at the early stage of infection in pregnant women. methods: 225 pregnant women, who were in the 2nd to 4th month of their pregnancy, enrolled i...

introduction: toxoplasma gondii (t. gondii) is distributed worldwide and infects most species. the serious incidence and severe or fatal injury caused by t. gondii infection clearly indicates the necessity for the event of a vaccine. the current study goals were to evaluate serological applications of toxoplasma gondiirhoptry protein 1 (rop1) antigen. materials and methods: we created a polymer...

background: the assays currently available for the detection of specific anti- toxoplasma antibodies may vary in their abilities to detect serum immunoglobulins, due to the lack of a purified standardized antigen. the aim of this study was evaluation the recombinant toxoplasma gondii sag1 antigen for the serodiagnosis of acute and chronic toxoplasmosis. methods : this study describes an elisa u...

Background and aims: Toxoplasmosis is a very common disease in the world. Two types of acquiredtoxoplasmosis have been detected. In the chronic toxoplasmosis, the abnormality of tissue functionis little but, in acute toxoplasmosis, function of RES system becomes interrupted. The assessment oftoxoplasma antibody with tissue enzymes in this stage is very important. Furthermore, ...

We studied the pathology of acute toxoplasmosis in experimental mice inoculated with RH strain tachyzoites of Toxoplasma gondii. All died from severe disseminated toxoplasmosis involving the liver, spleen and pancreas. Pathological features of acute toxoplasmosis in susceptible mice could be regarded as an excellent model for acute reactivation of Toxoplasma in the immunosuppressed host.

Background: The diagnostic methods which are used for acute ocular toxoplasmosis are very important; if the treatment is delayed, it sometimes leads to loss of vision. Fewstudies have been performed to evaluate serological tests used in the diagnosis of acute ocular toxoplasmosis. Objective: To evaluate the immunoglobulin (Ig) M, G and IgG avidity tests for dia...

Untreated acute toxoplasmosis among pregnant women can lead to serious sequelae among newborns, including neurological impairment and blindness. In Brazil, the risk of congenital toxoplasmosis (CTox) has not been fully evaluated. Our aim was to evaluate trends in acute toxoplasmosis prevalence from 1998-2005, the incidence of CTox and the rate of mother-to-child transmission (MTCT). A cross-sec...

We investigated 32 families of persons with acute toxoplasmosis in which > or = 1 other family member was tested for Toxoplasma gondii infection; 18 (56%) families had > or = 1 additional family member with acute infection. Family members of persons with acute toxoplasmosis should be screened for infection, especially pregnant women and immunocompromised persons.

background: the prevalence of toxoplasma gondii infection in the blood donors has been poorly studied. the aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. methods: a total of 250 blood products (112 fresh frozen plasma and 138 packed cells) in the blood transfusion institute, shiraz, iran were tested for spe-cific t. gondii antibodies (igg an...