background: it has been reported that liver function alterations occur in 8–38% of patients with relapsing-remitting multiple sclerosis (rrms) treated with interferon-beta in controlled clinical trials or in prospective but non-controlled studies. we report herein a case of symptomatic liver dysfunction associated with two-year-period of regular interferon-beta-1a (avonex®) intramuscular inject...

septicaemia caused by gram-negative pathogens is a dangerous infection which is associated with high incidence of liver dysfunction. the severe and acute hepatotoxicity is presumably due to massive release of endotoxin into systemic circulation after bacterial killing. the direct toxic effect of endotoxin is probably due to the increased production of reactive oxygen intermediates as o 2 - , pe...

Septicaemia caused by gram-negative pathogens is a dangerous infection which is associated with high incidence of liver dysfunction. The severe and acute hepatotoxicity is presumably due to massive release of endotoxin into systemic circulation after bacterial killing. The direct toxic effect of endotoxin is probably due to the increased production of reactive oxygen intermediates as O 2 - , p...

Liver dysfunction is one of the most recognized complications in patients with acute heart failure (HF) and therefore a liver function score may be useful for risk-stratification those patients. Recently, albumin-bilirubin (ALBI) was developed as new model to assess disease. We explored association between ALBI at admission in-hospital mortality HF.

objectives the main aim of this study was to evaluate the usefulness of applying extracorporeal liver support techniques to treat this group of patients. patients and methods the data from 23 hospital admissions of 21 patients with ald who were admitted to the department of anesthesiology and intensive therapy (a⁢) at the dr wł. biegański regional specialist hospital in łódź between march 20...

Background: It has been reported that liver function alterations occur in 8–38% of patients with relapsing-remitting multiple sclerosis (RRMS) treated with interferon-beta in controlled clinical trials or in prospective but non-controlled studies. We report herein a case of symptomatic liver dysfunction associated with two-year-period of regular interferon-beta-1a (Avonex®) intramuscular inje...

background: recent studies demonstrated that resveratrol has many therapeutic effects on liver disorders. resveratrol significantly increased survival after liver transplantation, decreased fat deposition, necrosis, and apoptosis which induced by ischemia in wistar rats. it provided liver protection against chemical, cholestatic, and alcohol injury. resveratrol can improve glucose metabolism an...

BACKGROUND We summarize our experience in the pathological diagnosis of late complications of liver transplantation (LT) to better understand the causes of late allograft dysfunction in a population mostly composed of patients with hepatitis B virus (HBV) infection. METHODS We reviewed 361 post-transplant liver biopsies from 174 patients who underwent LT and first presented with liver functio...