acute fatty liver of pregnancy (aflp) is a rare entity and a potentially fatal disorder. it is reported to be more common in multiple than singleton pregnancies. sometimes it coincides with preeclampsia but the exact etiology is not yet understood. a 31-year-old g2 p1 patient admitted at 33 weeks of pregnancy with signs and symptoms of jaundice, gastroenteritis, hypertension, malaise, urinary i...

Jaundice in pregnancy can be caused by viral hepatitis, intrahepatic cholestasis of pregnancy, choledocholithiases, HELLP syndrome (hemolysis, elevated liver enzymes, and a low platelet count), severe preeclampsia, and acute fatty liver of pregnancy. I Acute fatty liver of pregnancy occurs in approximately 1 in 13,000 pregnancies. More than 90% of patients with acute fatty liver of pregnancy ha...

conclusions in the current study, the clinical and paraclinical signs of aflp were mostly - liver, coagulation, kidney, and hypoglycemia disorders. considering that patients mostly refer in three phases of clinical, laboratory, and complications, it is essential to evaluate the suspected ones who present clinical symptoms especially nausea, vomiting and abdominal pain. patients and methods this...

A 39 year old woman was admitted to a maternity unit at 34 weeks' gestation with nausea, vomiting, and jaundice. Her condition deteriorated, and she was transferred to hospital, deeply unconscious and hypotensive. The diagnosis of acute fatty liver of pregnancy was initially suggested by the typical history of prodromal malaise and vomiting and the rapid onset of hepatic encephalopathy with pro...

Acute fatty liver of pregnancy is an uncommon, potentially fatal disorder that usually occurs in the third trimester of pregnancy or in the early post partum. We present here a 30-year-old Nigerian primigravida with acute fatty liver of pregnancy. She was successfully managed and discharged.

Preeclampsia, HELLP syndrome (hemolysis, elevated liver enzymes, and low-platelet count), and acute fatty liver of pregnancy are the main causes of thrombotic microangiopathy and evere liver dysfunction during pregnancy and represent different manifestations of the same pathological continuum. The case of a 35-week pregnant woman who was admitted to an intensive care unit immediately after a Ce...

Acute fatty liver of pregnancy is a rare and life-threatening disease associated with a defect in fatty acid metabolism in the fetus that causes liver disease in the mother. Prompt diagnosis and management are critical to the outcome of both the mother and the fetus and require involvement of several medical specialties, including hepatology, obstetrics, and, possibly, critical care. The includ...