the absence of cerebrospinal fluid (csf) pleocytosis in invasive meningococcal disease (imd) has been associated with an increased risk of death. it is unknown whether patients who lack a cellular response to central nervous system (cns) infection are at the same risk of adverse outcome as patiens without cns infection. to determine the frequency of presentation and outcome of three groups of c...

background: this study sought to access differences in long-term (9 months) outcomes between acute coronary syndrome (acs) patients who undergo early intervention compared to percutaneous coronary intervention (pci) in stable and refractory conditions. methods: data originated from tehran heart center registry- interventional cardiology (thcr-ic) and consisted of 1267 patients divided into two ...

background meningitis is a life-threatening disease and can lead to significant sequelae. pediatric bacterial meningitis leaves some survivors with more significant sequelae if not treated, promptly. the advent of vaccine has changed the incidence of pediatric bacterial meningitis but these vaccines have not been used in routine childhood immunization schedule. objectives the current study aime...

this study sought to compare the clinical features and outcome of a first acute myocardial infarction (ami) with onset of symptoms during or within 30 minutes of exercise, at rest and in bed. information collected using a standard questionnaire was used to relate activity at the onset of symptoms and in-hospital outcome in 500 consecutive patients admitted to our heart center with a first ami b...

High-sensitivity troponin (hs-cTn) assays enable the troponin cutoff value to be lowered, resulting in an increase of sensitivity at the cost of specificity. In the present study, the risk of a short-term adverse outcome was assessed in patients with acute pulmonary embolism (PE) using high-sensitivity troponin I (hs-cTnI). We used a cutoff value of 0.1 ng/ml in accordance with current guidelin...

to determine the factors affecting the outcome of patients with traumatic acute subdural hematoma, we reviewed the records of7 4 consecutive comatose patients with a glascow coma scale score (gcs) of less than 8 who had been admitted to imam hosein medical center from 1990 to 1996 and had undergone a uniform treatment protocol. the overall mortality rate was 73% and 23% had functional recovery,...

background: we aimed to explore whether maternal asymptomatic hepatitis b (hb) infection effects on pre-term rupture of membranous (prom), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. methods: we searched the pubmed, scopus, and isi web of science from 1990 to feb 2015. in addition, electronic literature searches supplemented by searching the gray lit...

the sex hormone progesterone has been shown to improve outcomes in animal models and two early-phase trials involving patients with traumatic brain injury (tbi). the aim of this clinical study was to assess the effect of progesterone on the improvement of neurologic outcome in patients with diffuse and acute tbi. a prospective, randomized, double-blind trial of progesterone was conducted in our...

background meningitis is an inflammation of the membranes, which surround the brain and spinal cord. early treatment of bacterial meningitis can prevent serious complications. in the last two decades, three vaccines have been developed against the three main bacterial species implicated in meningitis of children in western countries and vaccine-preventable invasive bacterial meningitis has decr...