BACKGROUND Exposure to sunlight may decrease the risk of several diseases through the synthesis of vitamin D, whereas solar radiation is the main cause of some skin and eye diseases. However, to the best of our knowledge, the association of sun-induced skin damage with mortality remains unknown. METHODOLOGY/PRINCIPAL FINDINGS Subjects were 8472 white participants aged 25-74 years in the First...

Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomitant temporal arteritis. Our case and review of the literature emphasize the association between actinic granuloma and temporal arteritis, a seriou...

Chronic oral breathing is characterized by respiratory and anatomic alterations found in children who breathe through their mouth only. Through open-mouth breathing, these patients develop anatomic deformities such as a typical adenoid facies. Such anatomic alterations make the lower lip of these patients more prone to UV action and its related actinic damage. This paper discusses an 11-year-ol...

Vitiligo is a common depigmentary disorder, with loss of epidermal Melanocytes as its hallmark. This absence of melanin hypothetically makes skin more susceptible to Chronic Actinic Damage (CAD) and skin cancer development. However, various studies have shown no increased incidence of skin cancer and some point to decreased actinic damage in skin with vitiligo. We studied 14 patients with vitil...

Non-melanoma skin cancer is the most common skin cancer with an incidence that varies widely worldwide. Among them, actinic keratosis (AK), considered by some authors as in situ squamous cell carcinoma (SCC), are the most common and reflect an abnormal multistep skin cell development due to the chronic ultraviolet (UV) light exposure. No ideal treatment exists, but the potential risk of their d...

Mr KC, 61 years of age, has extensive actinic damage including squamous cell carcinomas (SCCs) and actinic keratoses (AKs) on his face and forehead. He has had cryotherapy for many years with limited success. Lesions have generally resolved with cryotherapy but he finds the treatment very uncomfortable and can only tolerate a small number of lesions being treated on each visit. He develops lesi...

1. Rossi R, Mori M, Lotti T. Actinic keratosis. Int J Dermatol. 2007;46:895--904. 2. Schaefer I, Augustin M, Spehr C, Reusch M, Kornek T. Prevalence and risk factors of actinic keratoses in Germany----analysis of multisource data. J Eur Acad Dermatol Venereol. 2014;28:309--13. 3. Naldi L, Chatenoud L, Piccitto R, Colombo P, Placchesi EB, La Vecchia C, et al. Prevalence of actinic keratoses and ...

illions of vacationers deliberately expose themselves to excessive UV radiation. As a result, the risk of UVrelated skin damage is rapidly increasing. Sun worshippers thus have to expect an increased risk for actinic keratoses (a carcinoma in situ). Most recent estimates prove that about 8 million Germans suffer from actinic keratoses. There is an estimated prevalence of about 15 percent among ...

1. Rossi R, Mori M, Lotti T. Actinic keratosis. Int J Dermatol. 2007;46:895--904. 2. Schaefer I, Augustin M, Spehr C, Reusch M, Kornek T. Prevalence and risk factors of actinic keratoses in Germany----analysis of multisource data. J Eur Acad Dermatol Venereol. 2014;28:309--13. 3. Naldi L, Chatenoud L, Piccitto R, Colombo P, Placchesi EB, La Vecchia C, et al. Prevalence of actinic keratoses and ...

Actinic cheilitis is an oral potentially malignant disorder caused by UV radiation leading to damage epithelial keratinocytes of the lips. It predominantly affects vermillion border lower lip. Due its association with chronic exposure, associated risk factors include geographic areas, outdoor occupations, and skin subtypes. A high proportion lip squamous cell carcinomas arise from actinic lesio...