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introduction and aims: gastroesophageal reflux disease (gerd) is very common in western countries. gerd is increasing, has profound effects on health economics, disturbs the patient's health-related quality of life, and increases the risk for development of esophageal adenocarcinoma. gerd is considered to be infrequent in developing countries. this study was performed to determine the prevalenc...

background: gastroesophageal reflux disease (gerd) is one of the most prevalent disorders affecting gastrointestinal tract with a wide range of frequency around the world. in this study, we aimed to review all of the published studies about gerd’s prevalence in iran systematically. methods: we searched bibliographic databases including pubmed and google scholar and local databases (scientific i...

UNLABELLED Esophago-pharyngeal regurgitation is implicated in various otolaryngologic and respiratory disorders. The pathophysiological mechanisms causing regurgitation are still largely unknown. AIM To determine the principal mechanisms behind esophago-pharyngeal regurgitation. METHODS We studied 11 patients with extra-esophageal GORD symptoms in whom esophago-pharyngeal acid regurgitation...

BACKGROUND Following a pulmonary resection, some patients suffer from persistent coughing, which may have a relationship with acid regurgitation. Since few physiological studies have been reported regarding this issue, we conducted the present observational study. METHODS Persistent cough after pulmonary resection (CAP) was defined as non-productive coughing that occurred after a pulmonary re...

valvular heart lesions have deleterious effects on hemodynamics in parturients during pregnancy. cesarean section with an opioid-based general anesthesia is used to alleviate the adverse effects. we described a case of a 28-year-old primigravida at 37 weeks’ gestation with a diagnosis of severe mitral regurgitation, tricuspid regurgitation, and pulmonary hypertension in active labor. cesarean s...

OBJECTIVES To determine if a discrepancy exists between subjective symptoms and the grade of endoscopic gastroesophageal reflux disease (GERD) in diabetes mellitus (DM) patients. METHODS All 2,884 patients who underwent esophagogastroduodenoscopy completed the modified Gastrointestinal Symptom Rating Scale (GSRS), an interview-based rating scale consisting of 16 items including a question on ...

BACKGROUND The use of non-steroidal anti-inflammatory drugs (NSAIDs) is often associated with upper gastrointestinal symptoms such as heartburn and acid regurgitation. AIM To assess the efficacy of esomeprazole 20 and 40 mg for resolution of heartburn and acid regurgitation in continuous NSAIDs. METHODS A post hoc analysis of five clinical trials was performed. Two identically designed, pla...