نتایج جستجو برای: acetylgalactosamine

تعداد نتایج: 1087  

Journal: :The Journal of biological chemistry 1974
M Tsuji M Hamano Y Nakanishi K Ishihara S Suzuki

A soluble fraction from the isthmus region of hen oviduct catalyzes the liberation of SOF from UDP-N-acetylgalactosamine-4-sulfate (the nucleotide that accumulates in the same tissue during egg formation). The enzyme is purified some &fold and is shown to catalyze the reactions: (a) UDP-N-acetylgalactosamine-4-sulfate 4 UDP-N-acetylgalactosamine plus SOF; and (b) UDP-N-acetylgalactosamine-4,6-d...

Journal: :The Biochemical journal 1972
M Duckworth A R Archibald J Baddiley

The N-acetylgalactosamine in the walls of Bacillus subtilis 168 occurs in two polymers. One of these contains N-acetylgalactosamine, glucose and phosphorus and is attached to the peptidoglycan through an alkali-labile bond; preliminary studies indicate that a repeating unit of this polymer is glucosyl-N-acetylgalactosamine 1-phosphate. N-Acetylgalactosamine is also associated with the peptidogl...

2003
SAKARU SUZUKI

An enzymatic reaction has been identified in the isthmus of hen oviduct in which sulfate is transferred from 3’-phosphoadenosine 5’-phosphosulfate to mucopolysaccharide acceptors (1). From studies of the reaction with monosaccharides and oligosaccharides as model acceptors (‘2) it was concluded that one or more enzymes in the preparations employed catalyze a direct transfer of sulfate from PAPS...

Journal: :The Biochemical journal 1973
R G Lewis A F Spencer J E Silbert

Neoplastic mast cells of mice (including long-established and newly derived lines) were grown in large-volume suspension cultures to provide enough cells for preparation of microsomal fractions. Microsomal preparations from P815Y and P815S cells synthesized (14)C-labelled glycosaminoglycan when incubated with UDP-[(14)C]glucuronic acid and UDP-N-acetylgalactosamine. No significant amount of (14...

Journal: :The Journal of clinical investigation 2008
Hitoshi Suzuki Zina Moldoveanu Stacy Hall Rhubell Brown Huong L Vu Lea Novak Bruce A Julian Milan Tomana Robert J Wyatt Jeffrey C Edberg Graciela S Alarcón Robert P Kimberly Yasuhiko Tomino Jiri Mestecky Jan Novak

Aberrant glycosylation of IgA1 plays an essential role in the pathogenesis of IgA nephropathy. This abnormality is manifested by a deficiency of galactose in the hinge-region O-linked glycans of IgA1. Biosynthesis of these glycans occurs in a stepwise fashion beginning with the addition of N-acetylgalactosamine by the enzyme N-acetylgalactosaminyltransferase 2 and continuing with the addition o...

Journal: :Journal of Biological Chemistry 1957

Journal: :The Journal of biological chemistry 1957
C E CARDINI L F LELOIR

Several papers have been published on the biosynthesis of glucosamine in different organisms (l-3), but the reactions which lead to the synthesis of galactosamine have hardly been explored. The first indication of its mode of synthesis came from the isolation of uridine diphosphate’ acetylgalactosamine from liver by Pontis (4). This finding showed that the transformation of acetylhexosamines is...

Journal: :Histology and histopathology 2000
A M Bondi M G Gabrielli D Accili M G Sabbieti G Menghi

A confocal analysis was performed on the quail (Coturnix coturnix japonica) lingual salivary glands where the carbohydrate chains were studied by lectin histochemistry. For this purpose, appropriate FITC- and TRITC-conjugates were used for double binding also accomplished with sialidase digestion. The glycosidic components of the quail lingual salivary glands were found to be heterogeneously di...

Journal: :Journal of Biological Chemistry 1955

Journal: :Veterinary research 2001
F Parillo S Diverio L Todini O Fagioli

The changes that occur in the carbohydrate composition of zona pellucida glycoproteins during oocyte maturation in the wild-boar were studied using periodic-acid Schiff (PAS), High Iron Diamine (HID) and Low Iron Diamine (LID). Lectin staining was performed with a panel of 11 HRP-lectin conjugates combined with neuraminidase digestion and chemical treatments. There were few internal glucidic re...

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