نتایج جستجو برای: accumulated damage

تعداد نتایج: 262190  

Journal: :PLoS Biology 2006
María A Rujano Floris Bosveld Florian A Salomons Freark Dijk Maria A.W.H van Waarde Johannes J.L van der Want Rob A.I de Vos Ewout R Brunt Ody C.M Sibon Harm H Kampinga

Disease-associated misfolded proteins or proteins damaged due to cellular stress are generally disposed via the cellular protein quality-control system. However, under saturating conditions, misfolded proteins will aggregate. In higher eukaryotes, these aggregates can be transported to accumulate in aggresomes at the microtubule organizing center. The fate of cells that contain aggresomes is cu...

Journal: :Journal of biomechanics 2008
M Muller D Mitton M Talmant P Johnson P Laugier

Bone micro-damage is commonly accepted as a relevant parameter for fracture risk assessment, but there is no available technique for its non-invasive characterization. The objective of this work is to study the potential of nonlinear ultrasound for damage detection in human bone. Ultrasound is particularly desirable due to its non-invasive and non-ionizing characteristics. We show results illus...

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