Introduction: Nowadays, radioisotopes have a lot of therapeutic and diagnostic applications in nuclear medicine. The technetium-99m radioisotope is widely used in the diagnostic field. The technetium-99m radioisotope is widely used in the diagnostic field. In this study, in order to increase the absorption dose in thyroid cancer cells, the radioactive drug technetium-99m which ...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...

Relation to high absorption fraction of Tc sestamibi by kidneys in heart scan and these organs are near to generation organs (Ovaries and uterus). Urinary system (kidneys and urinary bladder) are specified as sources organs. The main object of this study is to determine the absorbed dose in these critical organs. we have set amount of absorbed fraction radiopharmaceutical in position of kidneys...

This paper describes the mathematical efficiency calibration of the whole-body counter at Forschungszentrum Jülich using Monte Carlo codes and mathematical anthropomorphic phantoms. As a prerequisite for the Monte Carlo simulations a precise model of the 4 high-purity germanium (HPGe) detectors had to be developed. Because the technical data provided by the manufacturer were not sufficient for ...

Background: Reliable estimation of radiation-absorbed dose is necessary to evaluate the benefits and the risks of radiopharmaceuticals used for diagnostic or therapeutic purposes in nuclear medicine. Materiel and Methods: This study included 47 patients treated with iodine-131 for Graves’ disease. A comparative study between Geant4 Monte Carlo simulation and MIRD formalism was carried out to ev...

68 Objective: In this study, we tried to estimate human absorbed dose of Ga-NODAGA-glycine as a new potential positron emission tomography (PET) renal agent based on the biodistribution data reported in healthy rats, and compare our estimation with the available absorbed dose data from technetium-99m-diethy99m lenetriaminepentaacetic acid ( Tc-DTPA). Subjects and Methods: The medical internal r...

background: radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. the scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (mird) method. at the end, the results of mird calculations were compared with thermoluminescent dosimeter (tld-100). ma...

Background: The same conversion factors (k-factors) of Single CT (SECT) are applied to estimate the Effective Dose (ED) in Dual Energy Computed Tomography (DECT). However, k-factors for different organs need independently validating DECT, due conditions DECT. Objective: This study aimed calculate organ dose and imaging protocols (liver, chest, cardiac, abdomen) male female phantoms. Material Me...

Background: Radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. The scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (MIRD) method. At the end, the results of MIRD calculations were compared with thermoluminescent dosimeter (TLD...

Introduction: Development of a novel radiopharmaceutical needs assessment of its biological- distribution in animal models, most commonly mice prior to its common application. This study describes the biodistribution and absorbed dose prediction 131I-MIBG in human organs after injection in mice.   Materials and Methods: In this research, 131I-MIBG radiopha...