objective : this study aimed to review papanicolaou (pap) smears in patients of shohada hospital in tehran. materials and methods :  a cross-sectional descriptive study was carried out and a database search of all pap smear reports from 1995 to 2005 at cytopathology department was reviewed. the abnormal pap smear reports based on the bethesda system were assessed. results : a total of 13315 pap...

conclusions the high prevalence of hpv in abnormal cytology underlines to the fact that the presence of hpv is a critical factor in the development of cervical cancer. the use of hpv dna techniques could actually become an effective and fast means of ascertaining the presence of hpv in abnormal cytology. results result showed a 100% presence of high risk hpv in all the samples with abnormal cyt...

background: sex workers and hiv seropositive women are at high risk of abnormal cervical cytology. the objective of this study was to compare the cervical cytology among three groups of women: active sex workers, hiv-infected women, and general population in iran. methods: this was a cross-sectional study performed in hazrat zeinab, lavan clinics and drop in center (dic) in shiraz, iran. this s...

Cervical cytology remains the principal screening method to detect pre-invasive and invasive cervical lesions. Management of abnormal cervical cytology depends on the risk of encountering a significant cervical lesion or high-grade cervical disease. These risks may vary in different areas across the country. Thus, determining the rate of significant cervical lesion associated with each type of ...

BACKGROUND This study examines the relationship among psychosocial factors, behavioral risks for abnormal cervical cytology, and abnormal cervical cytology. METHODS A self-administered questionnaire was used to measure perceived stress, discrimination, lifetime stressful events, optimism, social support, and psychological state. Women with normal Pap smears attending a primary care clinic and...

Human papillomavirus type 16 (HPV-16) is associated with abnormal Papanicolou smears, indicative of cervical intraepithelial neoplasia. HPV-16 is the most common genital HPV and is found in up to 40% of young women with normal cervical cytology. In order to investigate whether transcriptionally active HPV-16 infection is associated with abnormal cervical smears, a reverse transcription-nested P...

Background: Since cervical cancer is reportedly the seventh most frequent cancer in women in Saudi Arabia and the eighth most frequent cancer among women aged between 15 and 44 years, we wanted to determine the prevalence of abnormal cervical cytology among subfertile women attending the reproductive medicine unit of a tertiary care center in Saudi Arabia. Materials and Methods: This was a retr...

BACKGROUND Cervical cancer is regarded as the second highest cause of cancer deaths in Nigeria, with an overall prevalence similar to most developing countries. Screening for cervical cancer is primarily performed using papanicolaou (PAP) staining procedure, in Nigeria. OBJECTIVES This study aimed to use human papillomavirus (HPV) DNA typing, as a means of ascertaining the presence of high ri...

Objective: To evaluate the relationship between Loop Electrosurgical Excision Procedure (LEEP) margin status and subsequent cytology results to determine the significance of margin status as a predictor for recurrent cervical disease. Methods: A retrospective cohort of women who underwent LEEP for treatment of cervical dysplasia from 1995 to 2006 with subsequent follow-up to 2009 at a single ac...

AIM The purpose of the present study was to identify the role of abnormalities in DNA repair pathways by measuring the XPD and XRCC1 gene polymorphisms. MATERIALS AND METHODS Thirty-five patients with abnormal cervical cytology (study group) and 10 women with normal cytology (control group) were included in the study. The polymorphisms of XRCC1 Arg194Trp, XRCC1 Arg399Gln and XPD Lys751Gln gen...