نتایج جستجو برای: abcg1 abcg5 pyy 3

تعداد نتایج: 1812486  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه مازندران 1390

هدف از این مطالعه بررسی شش هفته تمرین هوازی با و بدون عصاره بنه (4 هفته، 1 میلی گرم به ازای هر کیلوگرم وزن بدن) روی بیان ژن abcg1، abcg5، ویسفاتین و pyy(3-36) در موش های صحرایی ماده.20 سر موش ماده (6-8 هفته ای 128-158 گرمی) که به طور تصادفی به گروه سالین کنترل، سالین تمرین، بنه کنترل و بنه تمرین تقسیم شدند. گروه های تمرینی به مدت شش هفته (5 روز در هفته، به مدت 60 دقیقه و سرعت 25 متر بردقیقه با ...

Journal: :Journal of lipid research 2004
F Jeffrey Field Ella Born Satya N Mathur

Possible mechanisms for the cholesterol-lowering effects of plant stanol esters were addressed by feeding hamsters diets containing stanol esters, cholesterol, or cholestyramine/lovastatin. ABCA1, ATP binding cassette G1 (ABCG1), ABCG5, ABCG8, and Niemann-Pick C1-like 1 (NPC1L1) mRNA levels were then estimated in duodenum, jejunum, and ileum. Plasma cholesterol was decreased by 36% and 94% in a...

Journal: :Journal of lipid research 2003
Weerapan Khovidhunkit Arthur H Moser Judy K Shigenaga Carl Grunfeld Kenneth R Feingold

Several of the ATP binding cassette (ABC) transporters have recently been shown to play important roles in reverse cholesterol transport (RCT) and prevention of atherosclerosis. In the liver, ABCG5 and ABCG8 have been proposed to efflux sterols into the bile for excretion. ABCG5 and ABCG8 also limit absorption of dietary cholesterol and plant sterols in the intestine. In macrophages, ABCA1 and ...

Journal: :Journal of lipid research 2001
G Schmitz T Langmann S Heimerl

The molecular cloning and identification of mutations in ATP-binding cassette transporters in hereditary diseases have greatly expanded our knowledge of the normal physiology of intracellular lipid transport processes. In addition to the well-known ATP-binding cassette transporter A1 (ABCA1) molecule, ABC transporters belonging to the ABCG (White) subfamily (ABCG1, ABCG5, and ABCG8) have been s...

Journal: :Circulation research 2006
John F Oram Ashley M Vaughan

A hallmark of atherosclerotic cardiovascular disease (CVD) is the accumulation of cholesterol in arterial macrophages. Factors that modulate circulating and tissue cholesterol levels have major impacts on initiation, progression, and regression of CVD. Four members of the ATP-binding cassette (ABC) transporter family play important roles in this modulation. ABCA1 and ABCG1 export excess cellula...

Journal: :The Journal of biological chemistry 2003
Menno Hoekstra J Kar Kruijt Miranda Van Eck Theo J C Van Berkel

Hepatic cholesterol(ester) uptake from serum coupled to intracellular processing and biliary excretion are important features in the removal of excess cholesterol from the body. ATP-binding cassette (ABC) transporters play an important role in hepatic cholesterol transport. The liver consists of different cell types, and ABC transporters may exert different physiological functions dependent on ...

2006
John F. Oram Ashley M. Vaughan

A hallmark of atherosclerotic cardiovascular disease (CVD) is the accumulation of cholesterol in arterial macrophages. Factors that modulate circulating and tissue cholesterol levels have major impacts on initiation, progression, and regression of CVD. Four members of the ATP-binding cassette (ABC) transporter family play important roles in this modulation. ABCA1 and ABCG1 export excess cellula...

2017
Alex Pizzini Lukas Lunger Egon Demetz Richard Hilbe Guenter Weiss Christoph Ebenbichler Ivan Tancevski

The beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cardiovascular disease have been studied extensively. However, it remains unclear to what extent n-3 PUFAs may impact Reverse Cholesterol Transport (RCT). RCT describes a mechanism by which excess cholesterol from peripheral tissues is transported to the liver for hepatobiliary excretion, thereby inhibiting foam cell f...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2004
Prasanth K Chelikani Alvin C Haver Roger D Reidelberger

We compared the effects of the two molecular forms of the brain-gut peptide YY (PYY), PYY(1-36) and PYY(3-36), on gastric emptying. Unanesthetized rats received 20-min intravenous infusions of rat PYY(1-36) (0, 1.7, 5, 17, 50, 100, 170 pmol x kg(-1) x min(-1)) and rat PYY(3-36) (0, 0.5, 1.7, 5, 17, 50, 100, 170 pmol x kg(-1) x min(-1)), either alone or combined, and gastric emptying of saline w...

Journal: :American journal of physiology. Endocrinology and metabolism 2007
Birgitte Sloth Louise Davidsen Jens Juul Holst Anne Flint Arne Astrup

Intraveneous (i.v.) PYY(3-36) infusions have been reported to reduce energy intake (EI) in humans, whereas few studies exist on effects of PYY(1-36). The aim of the present study was to examine effects of subcutaneous (sc) injections of PYY(1-36) and PYY(3-36) on appetite, ad libitum EI, plasma concentrations of PYY and free fatty acids (FFA) in obese males. Twenty-four males (BMI 27-40 kg/m(2)...

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