نتایج جستجو برای: Tartrazine

تعداد نتایج: 311  

Journal: :Allergologia et immunopathologia 1986
I Grzelewska-Rzymowska M Szmidt M L Kowalski J Roźniecki

The occurrence of sensitivity to tartrazine was examined in 51 patients with asthma and aspirin sensitivity. All patients underwent oral challenge tests with aspirin and tartrazine. Sensitivity to tartrazine was found in 16 i.e. 31.4% of tested asthmatics. The symptoms of sensitivity to tartrazine were similar to those of aspirin. Tolerance to tartrazine was induced in 5 aspirin and tartrazine ...

2013
Zhuokun Li Shanshan Song Liguang Xu Hua Kuang Shidong Guo Chuanlai Xu

We have developed an ultrasensitive indirect competitive enzyme-linked immunosorbent assay for the determination of tartrazine. Two carboxylated analogues of tartrazine with different spacer lengths, and one derivative from commercial tartrazine after a little chemical modification, were synthesized as haptens in order to produce antibodies specific to tartrazine. The effect of sulfonic acid gr...

Journal: :Regulatory toxicology and pharmacology : RTP 2007
Mostafa Ould Elhkim Fanny Héraud Nawel Bemrah Françoise Gauchard Tristan Lorino Claude Lambré Jean Marc Frémy Jean-Michel Poul

Tartrazine is an artificial azo dye commonly used in human food and pharmaceutical products. Since the last assessment carried out by the JECFA in 1964, many new studies have been conducted, some of which have incriminated tartrazine in food intolerance reactions. The aims of this work are to update the hazard characterization and to revaluate the safety of tartrazine. Our bibliographical revie...

2017
Stephanie K. Meyer Philip M.E. Probert Anne F. Lakey Andrew R. Axon Alistair C. Leitch Faith M. Williams Paul A. Jowsey Peter G. Blain George E.N. Kass Matthew C. Wright

Tartrazine is a food colour that activates the transcriptional function of the human oestrogen receptor alpha in an in vitro cell model. Since oestrogens are cholestatic, we hypothesised tartrazine will cause periportal injury to the liver in vivo. To test this hypothesis, tartrazine was initially administered systemically to mice resulting in a periportal recruitment of inflammatory cells, inc...

Journal: :Acta pharmacologica et toxicologica 1981
S E Hedman R G Andersson

Tracheal smooth muscle obtained from ovalbumin-sensitized guinea pigs contracted with micromolar concentrations of tartrazine and indomethacin. The contractions were slightly reduced by clemastine, but were completely blocked by the SRS-A antagonist FPL 55712. Arylsulfatase B, which is an enzyme that inactivates SRS-A, also abolished the contractions induced by tartrazine. Contractions induced ...

Journal: :The Journal of allergy and clinical immunology 1979
J G Gerber N A Payne O Oelz A S Nies J A Oates

The effect of tartrazine on prostaglandin production was evaluated in several in vitro systems in order to elucidate the interrelationship between aspirin-sensitive asthma and tartrazine. Unlike the nonsteroidal anti-inflammatory drugs, tartrazine did not inhibit cyclooxygenase activity in sheep seminal vesicles, guinea pig lung microsomes, and human platelets. Tartrazine had no effect on the a...

2011
Mervat M. Kamel Heba S. El-lethey

The current research aimed to determine the influence of different doses of exposure to tartrazine on levels of hyperactivity, anxiety, depression and anti-social behaviours in rats. Forty five weanling male Wistar rats were randomly assigned into 3 groups of 15, divided on 2 replicates and administered our treatment daily in drinking water at different concentrations; 0, 1% and 2.5% for a 16 w...

Journal: :Indian journal of medical sciences 1996
M S Bhatia

Allergy to tartrazine-containing psychotropic medication (especially antidepressants) had been reported. 20 patients of apparent allergy to tartrazine-containing alprazolam brands in 480 patients exposed to the dye are described. Rechallenge with non tartrazine-containing alprazolam brands did not produce the similar allergic reactions.

Journal: :Annals of allergy 1981
R E Desmond J J Trautlein

Tartrazine dye has been implicated in a variety of adverse reactions. There is a high correlation between aspirin sensitivity and tartrazine sensitivity but the reverse is exceedingly rare. Herewith is presented a case where repeated occult exposures to tartrazine yellow dye in a patient who could take aspirin with impunity was uncovered by a deduction. The ubiquitous nature and protean manifes...

2017
Latifa Khayyat Amina Essawy Jehan Sorour Ahmed Soffar

Tartrazine is a synthetic organic azo dye widely used in food and pharmaceutical products. The current study aimed to evaluate the possible adverse effect of this coloring food additive on renal and hepatic structures and functions. Also, the genotoxic potential of tartrazine on white blood cells was investigated using comet assay. Twenty adult male Wistar rats were grouped into two groups of 1...

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