b ackground : the emergence and rapid spread of metallo-beta-lactamase (mbl) producing acinetobacter spp. are of great concern worldwide due to limited treatment options. epidemiologic studies of the causing genes are important for prevention. methods :   in  this  study,  70  imipenem-resistant  acinetobacter  strains  were isolated from health care associated infections. these isolates were s...

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

background pseudomonas aeruginosa is one of the most important agents causing nosocomial infections worldwide. multidrug resistance of isolated bacteria from nosocomial infections makes it difficult and sometimes impossible to treat. objectives the aim of the present study was to investigate the antibiotic resistance and association between blaimp and blavim genes with resistance to meropenem a...

background carbapenemes are a good choice for treatment of infections caused by multidrug resistant pseudomonads aeruginosa. the emergence of carbapenem resistance has become a major problem in treatment of this organism especially among immunocompromised patients including burn patients. objectives the aim of this study was to investigate carbapenem-resistance mechanisms among burn patients in...

conclusions regarding the importance of metallo-beta-lactamase (mbl) produced by pseudomonas spp. isolated from hospitals, quick identification of clinical samples should be considered as an important and basic step to treat and control infections caused by pseudomonas spp. results strains with mic > 4 µg/ml were investigated by phenotypic and genotypic methods. in the current study the rate of...

background and objective : carbapenems are therapeutic choice against infections caused by gram-negative bacilli including strains of acinetobacter baumannii. resistance to these antibiotics is mediated by efflux pumps, porins, pbps and ß-lactamases. the aim of this study was to determine the possibility of existence of mbls, oxas and ges-1 betalactamase genes among clinical isolates of acineto...

background and objective: metallo-beta-lactamase (mbl)-mediated resistance is an emerging threat in hospital isolates of pseudomonas aeruginosa. there is not enough information from iran regarding the prevalence and the screening methods for such enzymes. the present study was undertaken to detect metallo betalactamase in strains of p. aeruginosa isolated from burned patientusingphenotypic meth...

conclusions epidemiological and regional evaluation of mbl-producing p. aeruginosa through simple and inexpensive methods should be considered for effective treatment of carbapenem-resistant p. aeruginosa infections. results amongst all the p. aeruginosa isolates, 58.7% were resistant to imipenem while 31.8%, 13.5% and 74.4% were resistant to meropenem, doripenem and ertapenem, respectively. am...