Journal:
:jundishapur journal of microbiology
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mansoureh shahbazi dastjerdeh department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran
shirin kouhpayeh department of immunology, school of medicine, isfahan university of medical sciences, isfahan, ir iran
faezeh sabzehei department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran
hossein khanahmad department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran; department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran. tel: +98-031337922487, fax: +98-031-3668859
mansour salehi department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran
zahra mohammadi department of genetics and molecular biology, school of medicine, isfahan university of medical sciences, isfahan, ir iran
conclusions our findings revealed that the zfn technology could be employed to overcome ampicillin resistance by the targeted disruption of the ampicillin resistance gene, which leads to inactivation of β-lactam synthesis. therefore, zfn technology could be engaged to decrease the antibiotic resistance issue with the construction of a zfn archive against different args. to tackle the resistance...