INTRODUCTION [(18)F]BAY94-9172 (Florbetaben) (Compound 8) is a positron emission tomography (PET) tracer that is currently in Phase III study for in vivo mapping of fibrillar amyloid β as a pathological hallmark for Alzheimer's disease. This work reports new methods for the synthesis of [(19)F]BAY94-9172 and its two different precursors and radiosynthesis of [(18)F]BAY94-9172 with the two precu...

Principal Investigator: Michael Pellin, Chemistry/Materials Science Divisions, Argonne National Laboratory, Argonne, IL 60439; (630) 252-3510; [email protected] Co-Investigators: Michael Savina, Chemistry/Materials Science Divisions, Argonne National Laboratory, Argonne, IL 60439; (630) 252-3514; [email protected] Claude Reed, Technology Development Division, Argonne National Laboratory, ...

The one-dimensional q-differential transformation was introduced in [8] for solving the ordinary qdifferential equations. Here, we present the definition and operation of the two-dimensional qdifferential transform. A distinctive feature of the q-differential transform is its ability to solve linear and nonlinear partial q-differential equations. Applied Mathematics and Computation 2011 (217) 9...

The rate of comorbidities not related to human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) among HIV-infected patients may be higher than expected. We assessed the incidence of comorbidities not related to HIV infection or AIDS by CD4 cell count and highly active antiretroviral therapy (HAART) use status in an HIV clinical practice. A total of 2824 patien...

This paper investigates how drivers affect the development of eco-innovation in firms. Our research classifies three categories: internal factors, market and institutional factors. Using a sample with 9172 firms from Spanish Innovation Survey Panel, we study impact for energy environmental efficiency objectives. utilizes combination two methods: Ordinal Logit Regression Models Artificial Neural...

Biocathodes in bioelectrochemical systems (BESs) can be used to convert CO2 into diverse organic compounds through a process called microbial electrosynthesis. Unfortunately, start-up of anaerobic biocathodes in BESs is a difficult and time consuming process. Here, a pre-enrichment method was developed to improve start-up of anaerobic facultatively autotrophic biocathodes capable of using catho...

We adapted the method of epitope mapping by site-directed masking, which was described for purified soluble antigens [Paus,D. and Winter,G. (2006) Proc. Natl Acad. Sci. USA, 103, 9172-9177.], to map the binding site of an inhibitory monoclonal antibody on the cell surface protein ecto-nucleotidase NTPDase3. Using homology modeling, we built a 3D structure of NTPDase3 and designed 21 single cyst...

OBJECTIVE To evaluate the association between rheumatoid arthritis (RA) and cardiovascular comorbidities, including hyperlipidemia, hypertension, and diabetes, in Taiwanese patients based on the data from medical records. MATERIALS AND METHODS A retrospective study was performed using the computerized medical records from a regional hospital located in southern Taiwan. A total of 2293 patient...

OBJECTIVE To determine the prevalence and risk factors of obstructive sleep apnoea syndrome (OSAS) in Chinese children using a two-phase community-based study design. METHODS Children from 13 primary schools were randomly recruited. A validated OSAS screening questionnaire was completed by their parents. Children at high risk of OSAS and a randomly chosen low-risk group were invited to underg...