نتایج جستجو برای: 549 cell line

تعداد نتایج: 1970969  

Journal: :journal of sciences, islamic republic of iran 2012
m.r. noori-daloii

the lung cancer is one of the most dangerous cancers and is also the leading cause of cancer death worldwide, accounting for about 1.3 million deaths annually. however in clinical practice, lung cancer therapies commonly do with chemotherapy, although it is hard because the lung cancer may progress to metastasis stage. the metastasis of lung cancer is highly dependent of expression of matrix me...

Journal: :زیست شناسی جانوری تجربی 0
شهلا روزبهانی دانشیار گروه زیست شناسی،دانشکده علوم، دانشگاه آزاد اسلامی واحد فلاورجان، اصفهان، ایران فاطمه علی پورفرد دانشجو دکتری تخصصی گروه زیست شناسی دانشکده علوم، دانشگاه آزاد اسالمی واحد دامغان، سمنان، ایران

abstract cytotoxic effect of extract leaves of t. kotschyanus boiss. & hohen on human lang cell. t. kotschyanus boiss. & hohen was used in traditional medicine such as anti-inflammation, antispasmodic and gastrointestinal aim of this study was to survey the cytotoxic effects the of ethanol of leave of thymus kotschyanus on a-549 cell line. t. kotschyanus was collected on spring 2014 from selsel...

M.R. Noori-Daloii

The lung cancer is one of the most dangerous cancers and is also the leading cause of cancer death worldwide, accounting for about 1.3 million deaths annually. However in clinical practice, lung cancer therapies commonly do with chemotherapy, although it is hard because the lung cancer may progress to metastasis stage. The metastasis of lung cancer is highly dependent of expression of matrix me...

Journal: :Molecules 2016
Omar Aristeo Peña-Morán María Luisa Villarreal Laura Álvarez-Berber Angélica Meneses-Acosta Verónica Rodríguez-López

Despite prevention and treatment options, breast cancer (BC) has become one of the most important issues in the present day. Therefore, the need for more specific and efficient compounds remains paramount. We evaluated four previously isolated aryltetralin lignans: 5'-demethoxy-β-peltatin-A-methylether (1), acetylpodophyllotoxin (2), 5'-demethoxydeoxypodophyllotoxin (3), and 7',8'-dehydroacetyl...

Journal: :Molecular medicine reports 2012
Shi-Ying Zheng Yin Li Dong Jiang Jun Zhao Jin-Feng Ge

The aim of the present study was to investigate the anticancer effect of quercetin (QC) in the human lung cancer cell line A-549 and further study the mechanism of apoptosis induction by QC. Low differentiation potential A-549 human lung cancer cells were treated with QC at different doses and for different times, and the growth inhibitory rates were detected by MTT assay. Apoptosis induced by ...

Journal: :Dalton transactions 2006
Yongmei Zhao Weijiang He Pengfei Shi Jianhui Zhu Lin Qiu Liping Lin Zijian Guo

A trinuclear 3N-chelated monofunctional platinum complex, [Pt3(HPTAB)Cl3](ClO4)3 (HPTAB = N,N,N',N',N'',N''-hexakis(2-pyridylmethyl)-1,3,5-tris(aminomethyl)benzene), has been structurally characterized, which binds to DNA and demonstrates much higher potency against the murine leukemia cell line (P-388) and the human nonsmall-cell lung cancer cell line (A-549) than cisplatin.

Journal: :medical journal of islamic republic of iran 0
monireh mohsenzadegan department of immunology, school of medicine, iran university of medical sciences, tehran, iran & cellular and molecular research center, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) nader tajik department of immunology, school of medicine, iran university of medical sciences, tehran, iran & cellular and molecular research center, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) zahra madjd oncopathology research centre and department of pathology, school of medicine, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) mehdi shekarabi department of immunology, school of medicine, iran university of medical sciences, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) mohammad m farajollahi cellular and molecular research center, iran university of medical sciences, tehran, iran, department of medical biotechnology, school of allied medical sciences, iran university of medical sciences, tehran, iran & food and drug laboratory, fardis, alسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

background: prostate cancer is one of the leading causes of cancer deaths among men. new gene expressed in prostate (ngep), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. because of its selective expression in prostate cancer cell surface, ngep is a potential immunotherapeutic target. to target the ngep in prostate cancer, it is essential to investigat...

Journal: :Chemical & pharmaceutical bulletin 2012
Lu Lu Jian-Chao Chen Yan Li Chen Qing Yuan-Yuan Wang Yin Nian Ming-Hua Qiu

Two new triterpenoids and a chromone glycoside, namely, 24-epi-cimigenol-3-one (1), foetinoside (2), cimifugin-4'-O-[6″-feruloyl]-β-D-glucopyranoside (3), together with 18 known compounds, were isolated from the rhizomes of Cimicifuga foetida L. collected in Guizhou Province, China. All of the compounds were identified by spectroscopic methods, as well as chemical methods. In the in vitro cytot...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2013
Maryam Hamzeloo Moghadam Farzaneh Naghibi Azadeh Atoofi Mitra Asgharian Rezaie Mahboobeh Irani Mahmoud Mosaddegh

Cytotoxic activity of gaillardin, a sesquiterpene lactone isolated from Inula oculus-christi L. (Asteraceae), was assessed in the human breast adenocarcinoma cell line MCF-7, human hepatocellular carcinoma cell line HepG-2, human non-small cell lung carcinoma cell line A-549, and human colon adenocarcinoma cell line HT-29, resulting in IC50 values of 6.37, 6.20, 4.76, and 1.81 microg/mL, respec...

Journal: :international journal of molecular and cellular medicine 0
neda moazzezy molecular biology unit, pasteur institute of iran, pasteur ave. 13164 tehran, iran.سازمان اصلی تایید شده: انستیتو پاستور ایران (pasteur institute of iran) mana oloomi molecular biology unit, pasteur institute of iran, pasteur ave. 13164 tehran, iran.سازمان اصلی تایید شده: انستیتو پاستور ایران (pasteur institute of iran) saeid bouzari molecular biology unit, pasteur institute of iran, pasteur ave. 13164 tehran, iran.سازمان اصلی تایید شده: انستیتو پاستور ایران (pasteur institute of iran)

shiga toxins (stxs) are bacterial virulence factors produced by shigella dysenteriae serotype 1 and escherichia coli strains. stxs are critical factors for the development of diseases such as severe bloody diarrhea and hemolytic uremic syndrome. additionally, stxs trigger the secretion of pro- inflammatory cytokines and chemokines, particularly in monocytes or macrophages. the inflammatory cyto...

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