The high-velocity oxygen-fuel (HVOF) spraying process was used to fabricate conventional WC-10Co-4Cr coatings and FeCrSiBMn amorphous/nanocrystalline coatings. The synergistic effect of cavitation erosion and corrosion of both coatings was investigated. The results showed that the WC-10Co-4Cr coating had better cavitation erosion-corrosion resistance than the FeCrSiBMn coating in 3.5 wt.% NaCl ...

Four V-Ta-4Cr-4Ti quaternary alloys containing different quantities of Ta were investigated to determine the effect content on Charpy impact properties. Five button-shaped ingots V-4Cr-4Ti ternary alloy and V-xTa-4Cr-4Ti (x = 3, 9, 15, 22 wt.%) fabricated a laboratory scale by using non-consumable arc-melting in an argon atmosphere. tests conducted at temperatures ranging from 77 K 293 instrume...

Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic acids and diamines in a bidirectional double Ugi-Four-Component (Ugi-4CR) based macrocyclization protocol. Alternatively, N-substituted cyclocholami...

The direct nonpeptidic macrocycle synthesis of α-isocyano-ω-amines via the classical Ugi four-component reaction (U-4CR) is introduced. Herein an efficient and flexible two-step procedure to complex macrocycles is reported. In the first step, the reaction between unprotected diamines and isocyanocarboxylic acids gives high diversity of unprecedented building blocks in high yield. In the next st...

Various V-Ta-4Cr-4Ti quaternary alloys containing different amounts of Ta were investigated to determine the effect concentration on their tensile properties. Six button-shaped ingots V-xTa-4Cr-4Ti (x = 4, 8, 15, 22, 24, and 35 wt.%) fabricated a laboratory scale by using non-consumable arc-melting in argon atmosphere. The sheet specimens for all examined herein obtained cold-rolling; hot-rolli...

Surface scratch has significant influence on the fatigue behavior of Ti-5Al-2Zr-4Mo-4Cr. In this paper, test with three different surface roughness are conducted, results recorded, including data and fracture characteristics. The distribution is analyzed characteristics discussed according to change roughness. Study Ti-5Al-2Zr-4Mo-4Cr intheoretical engineering study.

In this study, boron-containing primary amines were synthesized for use as building blocks in the study of peptoids. In the first step, Gabriel synthesis conditions were modified to enable the construction of seven different aminomethylphenyl boronate esters in good to excellent yields. These compounds were further utilized to build peptoid analogs via an Ugi four-component reaction (Ugi-4CR) u...

An improved total synthesis of (-)-julocrotine in three steps from Cbz-glutamine, in 51% overall yield, is presented. To demonstrate the potential of the heterocyclic moiety for diversity oriented synthesis, a series of (-)-julocrotine analogues was synthesized by employing the heterocyclic precursor as an amino input in Ugi four-component reactions (Ugi-4CR) [1].

This presentation discloses a one-pot synthesis of a series of spiropyrroloquinoline isoindolinone and spiropyrroloquinoline aza-isoindolinone scaffolds. The reaction proceeds by the combination of a Ugi four-component reaction (4CR) and two intramolecular cyclizations under metal-free conditions. The proof of the structures relies on analytical investigation and X-ray crystallography.

A three step synthesis of N-unsubstituted tetrazolo γ- and δ-lactams involving a key Ugi-4CR is presented. The compounds, otherwise difficult to access, are conveniently synthesized in overall good yields by our route. PDB analysis of the N-unsubstituted γ- and δ-lactam fragment reveals a strongly tri-directional hydrogen bond donor acceptor interaction with the amino acids of the binding sites.