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" VITAL ARTICLES ON SCIENCE/CREATION " *Dr. Daniel Criswell has a Ph.D. in molecular biology and is a biology professor at the ICR Graduate School. In 2001 the complete human genome was published 1 with great fanfare and excitement. Many anticipated that the knowledge of the human genetic code (the genome) would provide a complete understanding of what makes a human, well—human. In addition to ...
Event-related potential (ERP) approaches to social cognitive and affective neuroscience (SCAN) are not as widely used as other neuroimaging techniques, yet they offer several unique advantages. In particular, the high temporal resolution of ERP measures of neural activity make them ideally suited for studying the dynamic interplay of rapidly unfolding cognitive and affective processes. In this ...
The terminal differentiation of hypertrophic chondrocytes is a tightly regulated process that plays a pivotal role in endochondral ossification. As a negative regulator, Sox9 is essentially downregulated in terminally differentiated hypertrophic chondrocytes. However, the underlying mechanism of Sox9 silencing is undefined. Here we show that the zinc finger protein Zbtb20 regulates the terminal...
Despite extensive research it has proved difficult to establish the role of diet in the aetiology of common types of cancer. Obesity and alcohol definitely increase the risk for several types of cancer, but the importance of particular foods and nutrients is not clear. Part of the difficulty is our poor understanding of the physiological changes that might mediate the effect of diet on cancer r...
Variations in the expression of human pregnane X receptor (hPXR)– mediated cytochrome p450 3A4 (CYP3A4) in liver can alter therapeutic response to a variety of drugs and may lead to potential adverse drug interactions. We sought to determine whether Mg/Mndependent phosphatase 1A (PPM1A) regulates hPXR-mediated CYP3A4 expression. PPM1A was found to be coimmunoprecipitated with hPXR. Genetic or p...
USPC ................... 385/24; 385/14; 385/16; 385/18; 385/25; 385/34; 385/47; 385/129 (58) Field of ClassiTication Search USPC ........... 385/14, 16—18, 24, 25, 31, 33, 34, 47, 385/129—132 See application file for complete search history. (60) Provisional application No. 61/390, 837, filed on Oct. 7, 2010, provisional application No. 61/390, 876, filed on Oct. 7, 2010, provisional applicati...
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