نتایج جستجو برای: 371 h 980

تعداد نتایج: 537095  

2007
Masayuki Fukasawa Mika Kimura Sumiyo Morita Kenichi Matsubara Sumitaka Yamanaka Chiaki Endo Akira Sakurada Masami Sato Takashi Kondo Akira Horii Hiroyuki Sasaki Izuho Hatada

Affiliation 1. Laboratory of Genome Science, Biosignal Genome Resource Center, Department of Molecular and Cellular Biology, Gunma University, Maebashi 371-8511 Japan 2. PRESTO, Japan Science and Technology Corporation (JST), 4-1 Honmachi, Kawaguchi 332-0012, Japan 3. DNA Chip Research Inc., Yokohama, 230-0045, Japan 4. Department of Thoracic Surgery, Institute of Development, Aging and Cancer,...

Journal: :The Journal of pharmacology and experimental therapeutics 2014
Takato Hiranita Derek S Wilkinson Weimin C Hong Mu-Fa Zou Theresa A Kopajtic Paul L Soto Carl R Lupica Amy H Newman Jonathan L Katz

The present study examined RTI-371 [3β-(4-methylphenyl)-2β-[3-(4-chlorophenyl)-isoxazol-5-yl]tropane], a phenyltropane cocaine analog with effects distinct from cocaine, and assessed potential mechanisms for those effects by comparison with its constitutional isomer, RTI-336 [3β-(4-chlorophenyl)-2β-[3-(4-methylphenyl)-isoxazol-5-yl]tropane]. In mice, RTI-371 was less effective than cocaine and ...

2005
Eric K. Rowinsky G. Scott Long Dennis A. Noe Louise B. Grochow M. K. Bowling Susan E. Sartorius Ross C. Donehower

CI-980 (NSC 613862) is one of a novel class of 1,2dihydropyrido[3,4-bjpyrazines that inhibits tubulin polymerization, presumably by binding to the colchicine binding site of tubulin. In a Phase I and pharmacological study, 16 patients with advanced solid neoplasms were treated with CI-980 on a continuous 72-h infusion schedule at doses ranging from 3.0-5.4 mg/m2/day every 3 weeks. High rates of...

2007
Junko Iida Hiroyoshi Ishizaki Miki Okamoto-Tanaka Akira Kawata Kazutaka Sumita Shintaro Ohgake Yuji Sato Hiroshi Yorifuji Nobuyuki Nukina Kazumasa Ohashi Kensaku Mizuno Tomonari Tsutsumi Akira Mizoguchi Jun Miyoshi Yoshimi Takai Yutaka Hata

Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan; Department of Molecular Biology, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka 537-8511, Japan; Department of Neuromuscular and Developmental Anatomy, Graduate School of Medicine, Gunma University, 3-39-22 Showa-machi, Maebas...

2017
Kazuhisa Yuasa Daichi Takizawa Satoru Kakizaki

1Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan 2Department of Socio-Environmental Medicine, Public Health Division, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan 3Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency (JAEA), Takasaki, Gunma 370-1292, Japan *Correspo...

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