The metabolism of 5-fluorouracil (511) in tumors and livers of RII -1 tumor-bearing C3H mice given i.p. injections of 5FU was serially moni tored by "F magnetic resonance spectroscopy. The levels of 5FU and fluoronucleotide detected in the tumors after a dose of 130 mg/kg (n = 13) »ereless than one-third of those after 260-mg/kg 5FU (n = 14). During the days after these doses, tumor size decre...

Prutzman, P., Stern, L., Burger, M. L., & Bodenhamer, G. (1988). The friendly classroom for a small planet. Philadelphia: New Society Publishers. Sadalla, G., Holmberg, M., & Halligan, J. (1990). Conflict resolution: An elementary school curriculum. San Francisco: Community Boards. Selfridge, J. (2004). The Resolving Conflict Creatively Program: How we know it works. Theory into Practice, 43(1)...

2. Let G be a directed graph with source s and sink t. Suppose the capacities are specified not on the edges of G but on the vertices (other than s, t); for each vertex there is a fixed limit on the total flow through it. There is no restriction on flow through the edges. Show how to use the ordinary network flow theory to determine the maximum capacity of a feasible flow from s to t in the ver...

fant health outcomes, as well as reduced educational and employment opportunities for young mothers.2 Teenage pregnancy, early childbearing and adverse infant health outcomes are most likely to occur among disadvantaged women with restricted access to health services, but the social and economic pathways to these outcomes are not well understood.3 A great deal of attention has been focused on t...

Dietary restriction (DR) has been shown to extend both median and maximum lifespan in a range of animals, although recent findings suggest that these effects are not universally enjoyed across all animals. In particular, the lifespan effect following DR in mice is highly strain-specific and there is little current evidence that DR induces a positive effect on all-cause mortality in non-human pr...

We investigate the thickness and seismic velocity structure of the Rukwa Rift crust by modeling seismograms from the 1994 Mw 5.9 Rukwa earthquake and teleseismic receiver functions recorded on a broadband seismic station at the southeastern end of the rift. Two methods have been used to model receiver functions, Hstacking and waveform inversion, yielding Moho depth estimates of 34 ± 2 km (Hstac...

This project was designed to characterize olfactory tissue-specific proteins previously identified with a library of monoclonal antibodies raised against frog olfactory cilia. First, we showed that our olfactory tissue-specific monoclonal antibodies all recognize different molecular forms of the same protein. We named this protein "olfactomedin". We then proceeded to purify olfactomedin and cha...

A series of experiments, performed at Johns Hopkins University, which led to our finding that plasticizers are extracted from poly-(vinyl chloride) (PVC) plastic by blood and biologic fluids will be described. The experiments began with the appearance of an unknown compound in the isolated perfused liver system. Livers were perfused with a mixture of synthetic plasma containing bovine serum alb...

The study was a retrospective abattoir survey, undertaken for a period of one full year at the main traditional abattoir of Ismailia city, Egypt. During the survey, 9880 male cattle were slaughtered and inspected. As a result of postmortem inspections, 8 (0.10%) carcasses were totally condemned and 1456 (14.7%) organs had pathological lesions. Of the 1456 edible organs had pathological lesions;...