introduction:  the  use  of  mobile  communication  systems  has  dramatically  increased  over  the  past  decade. although many studies have been performed to determine the effect of radio frequency (rf) but  less attention has been paid to the possible biological impact of exposure to extremely low frequency  (elf) components.   the objective of this study is two folds. one is to design the ...

electromagnetic field (emf) radiation affects cellular and brain chemistry and function, resulting in deleterious effects such as free radicals formation, impaired dna repair, reduced melatonin and blood brain barrier protection, and defects on learning and memory and other higher brain functions. in this paper the effects of low frequency emf of 50- and 217 hz, ranges often associated with com...

Introduction:  The  use  of  mobile  communication  systems  has  dramatically  increased  over  the  past  decade. Although many studies have been performed to determine the effect of radio frequency (RF) but  less attention has been paid to the possible biological impact of exposure to extremely low frequency  (ELF) components.   The objective of this study is two folds. One is to design the ...

Introduction: Electrochemotherapy (ECT) is a cancer treatment modality to permeabilize cell membrane facilitating the non-permeant molecules to gain access to the cytosol of cells. Nevertheless, environmental electromagnetic fields (EMFs) may disturb the efficiency of ECT. The present study aimed to investigate the effect of EMFs 900 MHz pulse-modulated by 217 Hz extremely low-frequency fields ...

Connexins (Cx) are membrane proteins able to influence trophoblast functions. Here we investigated the effect of high-frequency electromagnetic fields (HF-EMF) on Cx expression and localization in extravillous trophoblast cell line HTR-8/SVneo. We also analysed cell ultrastructural changes induced by HF-EMF exposure. Samples were exposed to pulse-modulated 1817 MHz sinusoidal waves (GSM-217 Hz;...

We demonstrate a photon-counting optical time-domain reflectometry with 42.19 dB dynamic range using an ultra-low noise up-conversion single photon detector. By employing the long-wave pump technique and a volume Bragg grating, we achieve a noise equivalent power of -139.7 dBm/√Hz for our detector. We perform the OTDR experiments using a fiber of length approximate 217 km, and show that our sys...

Employment or Leadership: None declared. Consultant or Advisory Role: F.C. Wu, Organon International, Bayer Schering Pharma, Eli Lilly, Proctor & Gamble, Pierre Fabre Medicaments, Ferring Pharmaceuticals, TAP Pharmaceuticals, Ardana Bioscience, and GlaxoSmithKline. Stock Ownership: None declared. Honoraria: F.C. Wu, Organon International, Bayer Schering Pharma, Lilly ICOS, Ardana Bioscience, an...

5-[(2-Chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4(4-pyrimidinyl)isoxazole (AKP-001) is a potent p38 mitogen-activated protein kinase inhibitor that is being developed to specifically target the intestines for the treatment of inflammatory bowel disease. According to the ante-drug concept, AKP-001 was designed to be metabolized to inactive forms via the first-pass metabolism to avoid...