The compound 2-pyridinethiol, 1-oxide and its salts have been reported to have pronounced antibacterial and antifungal activity of a type that, were it a microbiological product, would cause it to be classed as a broad-spectrum antibiotic (5, 8). This property is shared by a number of other cyclic thiohydroxamic acids, variously substituted, though some are much more active than others. The hig...

Cephalosporins are chemotherapeutic agents whose spectrum and use are limited to antibacterial activity. Therefore, it was of interest to find several new semisynthetic cephalosporins which possess in vitro antifungal activity against Trichophyton mentagrophytes, Candida albicans and certain other yeasts. Five new cephalosporins containing the 2-pyridinethiol 1-oxide grouping were examined. Fou...

A carbon-past electrode modified with iron(II) phathalocyanine (FePc) was used as a sensitive potentiometric sensor for determination of 2-pyridinethiol (2PT). 2-mercaptoethanol (2ME) and sulfide ion in aqueous solutions. The modified electrode acts as an electrocatalyst for oxidation of these compounds, and lowers the overpotential for oxidation reactions by more than 400 mV, compared to t...

a carbon-past electrode modified with iron(ii) phathalocyanine (fepc) was used as a sensitive potentiometric sensor for determination of 2-pyridinethiol (2pt). 2-mercaptoethanol (2me) and sulfide ion in aqueous solutions. the modified electrode acts as an electrocatalyst for oxidation of these compounds, and lowers the overpotential for oxidation reactions by more than 400 mv, compared to the u...