Recently, matrix metalloproteinases (MMP), in particular the gelatinases MMP-2 and MMP-9, generally considered as tumor markers for clinical applications. A longitudinal 2-years follow-up survey was performed on dogs with cutaneous tumor. Serum samples were obtained from 22 dogs with different cutaneous tumors and 22 health dogs at the time of surgery and one month, three months and one year af...

dilated cardiomyopathy (dcm) is accompanied by myocytes and connective tissue changes. matrix metalloproteinases (mmps) play important roles in cardiac remodeling. it seems that the gelatinases (mmp-2 and mmp-9) are effective enzymes in cardiomyopathy. dilated cardiomyopathy was confirmed in 22 dogs (patient group) including 11 female and 11 male by clinical examination, auscultation, thoracic ...

Introduction:Oral Squamous Cell Carcinoma (OSCC) is an invasive neoplasm with a high prevalence. Matrix Metalloproteinase (MMP) has been thought to play an important role in both the invasion and metastasis of tumors. The aim of this study was to explore the significance of MMPs expression in clinical outcome of these patients. Materials:The most recognized data Bases such as PubMed, Google sc...

Upregulation of matrix metalloproteinases (MMPs), in particular MMP-2 and MMP-9 contributes to secondary pathogenesis of spinal cord injury (SCI) via promoting inflammation. Recently, we reported that trehalose suppresses inflammatory responses following SCI. Therefore, we investigated the effect of trehalose on MMP-2 and MMP-9 expression in SCI. A weight-drop contusion SCI was induced in male ...

Dilated cardiomyopathy (DCM) is accompanied by myocytes and connective tissue changes. Matrix metalloproteinases (MMPs) play important roles in cardiac remodeling. It seems that the gelatinases (MMP-2 and MMP-9) are effective enzymes in cardiomyopathy. Dilated cardiomyopathy was confirmed in 22 dogs (patient group) including 11 female and 11 male by clinical examination, auscultation, thoracic ...

introduction: exercise training increases skeletal muscle capillary density, but the molecular mechanisms of this process are not yet clear. the aim of the present study was to investigate the effect of acute long- term submaximal exercise on serum vascular endothelial growth factor (vegf) as the main angiogenic factor, and matrix metalloproteinases 2 and 9 ( mmp-2 and mmp-9), as the degrading ...

background: one of the most major obstacles of ovarian tissue vitrification is suboptimal developmental competence of follicles. matrix metalloproteinases 2 (mmp-2) and 9 (mmp-9) and their tissue inhibitors timp-1 and timp-2 are involved in the remodeling of the extracellular matrix in the ovaries. objective: this study aimed to evaluate the expression of mmp-2, mmp-9, timp-1, and timp-2 genes ...

conclusions: lymphatic metastasis in patients with oral and maxillofacial scc is closely related to the positive expression of vegf, mmp-9 and timp-2. mmp-9 and timp-2 can affect the progression of cancer, which is valuable for studies on oral and maxillofacial scc genes. objectives: to explore the association between expression of vegf, mmp-9 and timp-2 in oral and maxillofacial scc and clinic...